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1000 Titel
  • Risk factors and surgical outcomes in pediatric patients with congenital heart disease and ischemic colitis
1000 Autor/in
  1. Mokhaberi, N. |
  2. Schneider, E. P. |
  3. Aftzoglou, M. |
  4. Hüners, I. |
  5. Körner, M. |
  6. Armbrust, L. |
  7. Biermann, D. |
  8. Kozlik-Feldmann, R. |
  9. Hübler, M. |
  10. Reinshagen, K. |
  11. Tomuschat, C. |
1000 Verlag Springer Berlin Heidelberg
1000 Erscheinungsjahr 2024
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-12-26
1000 Erschienen in
1000 Quellenangabe
  • 41(1):48
1000 Copyrightjahr
  • 2024
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00383-024-05950-3 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11671421/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:sec> <jats:title>Introduction</jats:title> <jats:p>This study investigates risk factors and surgical outcomes in pediatric patients with congenital heart defects (CHD) who develop ischemic colitis (IC). Previous research indicates a higher IC risk in very low birth weight neonates with CHD.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>A retrospective analysis compared an IC-CHD group to a CHD-only group. Key variables included gestational age, birth weight, multiple pregnancies, prematurity, APGAR scores, cardiac and surgical characteristics, Aristotle-Score, and mortality rates. Surgical outcomes such as bowel resection and stoma procedures were also evaluated.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>IC-CHD exhibited significantly lower gestational ages and birth weights, with higher rates of multiple pregnancies and prematurity. APGAR scores were notably lower. Cardiac and surgical data showed more frequent ECMO use and shorter cardiopulmonary bypass durations in the IC-CHD group. High rates of bowel resection highlighted severe gastrointestinal involvement. Mortality was significantly higher in IC-CHD with elevated Aristotle scores correlating with poorer outcomes.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusion</jats:title> <jats:p>Gestational age, birth weight, and initial health status are critical in predicting IC risk and surgical outcomes in pediatric patients with CHD. The significantly higher mortality and complex surgical needs in the IC-CHD group underscore the necessity for vigilant monitoring and tailored interventions. Development of targeted therapeutic strategies adjustment for confounding factors in future studies is needed.</jats:p> </jats:sec>
1000 Sacherschließung
lokal Birth Weight [MeSH]
lokal Infant, Newborn [MeSH]
lokal Female [MeSH]
lokal Heart Defects, Congenital/mortality [MeSH]
lokal Congenital heart defect
lokal Humans [MeSH]
lokal Treatment Outcome [MeSH]
lokal Retrospective Studies [MeSH]
lokal Heart Defects, Congenital/surgery [MeSH]
lokal Risk Factors [MeSH]
lokal Bowel ischemia
lokal Ischemic colitis
lokal Original Article
lokal Necrotizing enterocolitis
lokal Infant [MeSH]
lokal Male [MeSH]
lokal Colitis, Ischemic/surgery [MeSH]
lokal Gestational Age [MeSH]
lokal Pediatric
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1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/TW9raGFiZXJpLCBOLg==|https://frl.publisso.de/adhoc/uri/U2NobmVpZGVyLCBFLiBQLg==|https://frl.publisso.de/adhoc/uri/QWZ0em9nbG91LCBNLg==|https://frl.publisso.de/adhoc/uri/SMO8bmVycywgSS4=|https://frl.publisso.de/adhoc/uri/S8O2cm5lciwgTS4=|https://frl.publisso.de/adhoc/uri/QXJtYnJ1c3QsIEwu|https://frl.publisso.de/adhoc/uri/Qmllcm1hbm4sIEQu|https://frl.publisso.de/adhoc/uri/S296bGlrLUZlbGRtYW5uLCBSLg==|https://frl.publisso.de/adhoc/uri/SMO8YmxlciwgTS4=|https://frl.publisso.de/adhoc/uri/UmVpbnNoYWdlbiwgSy4=|https://frl.publisso.de/adhoc/uri/VG9tdXNjaGF0LCBDLg==
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1000 Label
1000 Förderer
  1. Universitätsklinikum Hamburg-Eppendorf (UKE) |
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  1. -
1000 Förderprogramm
  1. -
1000 Dateien
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    1000 Förderer Universitätsklinikum Hamburg-Eppendorf (UKE) |
    1000 Förderprogramm -
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1000 Erstellt am 2025-02-04T18:23:19.405+0100
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