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1000 Titel
  • Temporomandibular disorders in individuals with Marfan syndrome: an exploratory analysis
1000 Autor/in
  1. Jenabzadeh, Termeh |
  2. Bohner, Lauren |
  3. Köppe, Jeanette |
  4. Kleinheinz, Johannes |
  5. Hanisch, Marcel |
  6. Oelerich, Ole |
1000 Verlag BioMed Central
1000 Erscheinungsjahr 2024
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-04-24
1000 Erschienen in
1000 Quellenangabe
  • 20(1):26
1000 Copyrightjahr
  • 2024
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s13005-024-00427-z |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11040890/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>This study aims to analyze to what extent patients with Marfan syndrome (MFS) are affected by temporomandibular disorders (TMD) and its impact on oral health-related quality of life (OHRQoL). To collect data, an online questionnaire was created to recruit participants from Germany, Austria, and Switzerland through social media and support groups. The questionnaire consists of free-text questions, the German versions of the Oral Health Impact Profile (OHIP-G14), the Depression Anxiety Stress Scale (DASS), and the Graded Chronic Pain Status (GCPS).</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>A total of 76 participants with diagnosed MFS were included. Of these, 65.8% showed TMD symptoms, the most common being pain or stiffness of the masticatory muscles in the jaw angle (50.0%). Only 14.5% of the participants were already diagnosed with TMD. Of the participants with an increased likelihood of a depression disorder, 76.9% showed TMD symptoms. Of those with a critical score for an anxiety disorder, 90.9% showed TMD symptoms. 73.3% of participants with TMD symptoms reached the critical score for a stress disorder. TMD symptoms were associated with a higher risk for chronic pain. In the median, participants with TMD showed statistically notably higher OHIP-G14 scores than participants without TMD (11.5 [IQR 17] vs. 1 [IQR 3] points, <jats:italic>p</jats:italic> ≤ 0.001).</jats:p> </jats:sec><jats:sec> <jats:title>Conclusion</jats:title> <jats:p>TMD symptoms had a noticeable impact on OHRQoL in patients with MFS, i.e., chronic pain and psychological impairment. TMD seems underdiagnosed, and more research is needed to prevent the associated chronification of pain and psychological burden to improve the OHRQoL.</jats:p> </jats:sec>
1000 Sacherschließung
lokal Surveys and Questionnaires [MeSH]
lokal Female [MeSH]
lokal Switzerland/epidemiology [MeSH]
lokal Psychological impairment
lokal Adult [MeSH]
lokal Marfan syndrome
lokal Humans [MeSH]
lokal Temporomandibular Joint Disorders/etiology [MeSH]
lokal Middle Aged [MeSH]
lokal Germany/epidemiology [MeSH]
lokal Oral health
lokal Male [MeSH]
lokal Marfan Syndrome/physiopathology [MeSH]
lokal Quality of Life [MeSH]
lokal Research
lokal Temporomandibular Joint Disorders/physiopathology [MeSH]
lokal Young Adult [MeSH]
lokal Temporomandibular Joint Disorders/psychology [MeSH]
lokal Austria/epidemiology [MeSH]
lokal Oral Health [MeSH]
lokal Marfan Syndrome/complications [MeSH]
lokal Chronic pain
lokal Marfan Syndrome/psychology [MeSH]
lokal Temporomandibular disorders
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/SmVuYWJ6YWRlaCwgVGVybWVo|https://frl.publisso.de/adhoc/uri/Qm9obmVyLCBMYXVyZW4=|https://frl.publisso.de/adhoc/uri/S8O2cHBlLCBKZWFuZXR0ZQ==|https://frl.publisso.de/adhoc/uri/S2xlaW5oZWlueiwgSm9oYW5uZXM=|https://frl.publisso.de/adhoc/uri/SGFuaXNjaCwgTWFyY2Vs|https://frl.publisso.de/adhoc/uri/T2VsZXJpY2gsIE9sZQ==
1000 Hinweis
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1000 Label
1000 Förderer
  1. Universitätsklinikum Münster |
1000 Fördernummer
  1. -
1000 Förderprogramm
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1000 Dateien
1000 Förderung
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    1000 Förderer Universitätsklinikum Münster |
    1000 Förderprogramm -
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1000 Objektart article
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1000 Erstellt am 2025-02-05T18:44:13.261+0100
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1000 Zuletzt bearbeitet 2025-09-11T16:26:55.371+0200
1000 Objekt bearb. Thu Sep 11 16:26:55 CEST 2025
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