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1000 Titel
  • International expert consensus on micronutrient supplement use during the early life course
1000 Autor/in
  1. Cetin, Irene |
  2. Devlieger, Roland |
  3. Isolauri, Erika |
  4. Obeid, Rima |
  5. Parisi, Francesca |
  6. Pilz, Stefan |
  7. van Rossem, Lenie |
  8. Maternal Nutrition Delphi Study Group |
  9. Steegers-Theunissen, Régine |
1000 Verlag BioMed Central
1000 Erscheinungsjahr 2025
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2025-01-20
1000 Erschienen in
1000 Quellenangabe
  • 25(1):44
1000 Copyrightjahr
  • 2025
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12884-024-07123-5 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11744953/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background</jats:title> <jats:p>Growing evidence demonstrates that maternal nutrition is crucial for the health of the mother-to-be, and early life course of the offspring. However, for most micronutrients, guidelines are inconsistent. This Delphi study aimed to investigate the level of expert consensus on maternal nutrition and micronutrient needs during preconception, pregnancy and lactation.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods</jats:title> <jats:p>We conducted a two-round web-based Delphi survey on various topics including general approaches to diet and supplement use, and existing guidelines. For the periods of preconception, pregnancy and lactation, questions focused on the importance and strength of evidence for supplement use with the following micronutrients for low- and high-risk populations: folic acid, choline, iodine, magnesium, calcium, iron, selenium, docosahexaenoic acid (DHA), and vitamins B1, B2, B6, B12, D and K.</jats:p> </jats:sec> <jats:sec> <jats:title>Results</jats:title> <jats:p>Thirty-five experts participated in the panel, who were healthcare professionals (HCPs), researchers and joint HCP-researchers with expertise in nutrition, gynaecology and/or obstetrics. Panellists reached consensus on the importance of diet and dietary supplement use during pregnancy and agreed on the lack of clarity and consistency in current guidelines, and the need for education in these areas for HCPs, pregnant people and the general population. For general low-risk populations, there was consensus on the importance of supplement use with iron and vitamin D from preconception through lactation, with folic acid and iodine from preconception through the second and third trimesters, respectively, with DHA from the first trimester through lactation and with calcium during lactation. Panellists agreed that the evidence for supplement use with each of these micronutrients during these phases to improve outcomes and/or foetal development is strong, except for vitamin D (preconception), DHA (first trimester), and iron (both periods). There was also consensus that supplement use advice should be tailored for people following vegan/vegetarian diets, restricted diets due to food intolerances, obesity, polycystic ovary syndrome, diabetes mellitus, and previous nutrition-related pregnancy complications.</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusion</jats:title> <jats:p>The findings revealed robust consensus on various aspects of maternal nutrition, including the need for education, the lack of consistency in current guidelines on supplement use, the importance of supplement use across specific phases of pregnancy and the at-risk groups requiring tailored approaches.</jats:p> </jats:sec>
1000 Sacherschließung
lokal Maternal Nutritional Physiological Phenomena [MeSH]
lokal Female [MeSH]
lokal Pregnancy
lokal Adult [MeSH]
lokal Humans [MeSH]
lokal Guidelines
lokal Preconception
lokal Lactation [MeSH]
lokal Preconception Care/standards [MeSH]
lokal Trace-elements
lokal Maternal diet
lokal Micronutrients/administration
lokal Dietary Supplements [MeSH]
lokal Nutritional Requirements [MeSH]
lokal Research
lokal Lactation
lokal Vitamins
lokal Delphi Technique [MeSH]
lokal Pregnancy [MeSH]
lokal Consensus [MeSH]
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1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/Q2V0aW4sIElyZW5l|https://frl.publisso.de/adhoc/uri/RGV2bGllZ2VyLCBSb2xhbmQ=|https://frl.publisso.de/adhoc/uri/SXNvbGF1cmksIEVyaWth|https://frl.publisso.de/adhoc/uri/T2JlaWQsIFJpbWE=|https://frl.publisso.de/adhoc/uri/UGFyaXNpLCBGcmFuY2VzY2E=|https://frl.publisso.de/adhoc/uri/UGlseiwgU3RlZmFu|https://frl.publisso.de/adhoc/uri/dmFuIFJvc3NlbSwgTGVuaWU=|https://frl.publisso.de/adhoc/uri/TWF0ZXJuYWwgTnV0cml0aW9uIERlbHBoaSBTdHVkeSBHcm91cA==|https://frl.publisso.de/adhoc/uri/U3RlZWdlcnMtVGhldW5pc3NlbiwgUsOpZ2luZQ==
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