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1000 Titel
  • Propensity Score-matched Comparison of WEB 17 and WEB 21 with 4–7 mm Device Sizes for the Treatment of Unruptured Intracranial Aneurysms
1000 Autor/in
  1. Goertz, Lukas |
  2. Liebig, Thomas |
  3. Siebert, Eberhard |
  4. Zopfs, David |
  5. Pennig, Lenhard |
  6. Schlamann, Marc |
  7. Radomi, Alexandra |
  8. Dorn, Franziska |
  9. Kabbasch, Christoph |
1000 Verlag Springer Berlin Heidelberg
1000 Erscheinungsjahr 2024
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-06-19
1000 Erschienen in
1000 Quellenangabe
  • 34(4):841-850
1000 Copyrightjahr
  • 2024
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00062-024-01430-2 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11564397/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:sec> <jats:title>Purpose</jats:title> <jats:p>The WEB 17 system represents the fifth generation of Woven Endobridge (WEB) flow disruptors and features a low profile with fewer wires than its predecessor, the WEB 21. The present study compares the safety and efficacy of the WEB 17 and WEB 21 for the treatment of unruptured cerebral aneurysms with 4–7 mm device sizes, which were available for both systems.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>Patient and aneurysm characteristics, complications, clinical outcome and angiographic results were retrospectively analysed. 1:1 propensity score matching was performed to adjust for minor baseline differences between the groups.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>Sixty aneurysms treated with WEB 21 and 90 with WEB 17 were included. The overall failure rate (deployment failure and adjunctive stent) was significantly higher with WEB 21 (16.7%) than with WEB 17 (3.3%, <jats:italic>p</jats:italic> &lt; 0.01). The rates of neurological events between WEB 21 (6.7%) and WEB 17 treatment (1.1%) were not significantly different (<jats:italic>p</jats:italic> = 0.08). Also, procedural morbidity was comparably low in both groups (WEB 21: 3.3%, WEB 17: 0%, <jats:italic>p</jats:italic> = 0.16). The rates of complete/adequate occlusion at follow up were 69.7%/86.4% for WEB 17 vs. 80.4%/91.3% for WEB 21 at short-term (<jats:italic>p</jats:italic> = 0.27), and 64.5%/83.9% vs. 75.9%/86.2% at mid-term (<jats:italic>p</jats:italic> = 0.41), respectively. Propensity score matching confirmed the results of the unmatched series.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusion</jats:title> <jats:p>WEB 17 and WEB 21 had a similar safety and efficacy profile, but WEB 17 was associated with an improved feasibility. Prospective studies with long-term follow-up will define the full potential of the WEB 17 system.</jats:p> </jats:sec>
1000 Sacherschließung
lokal Female [MeSH]
lokal Endovascular Procedures/instrumentation [MeSH]
lokal Stents [MeSH]
lokal Aged [MeSH]
lokal Endovascular Procedures/methods [MeSH]
lokal Adult [MeSH]
lokal Endovascular
lokal Embolization, Therapeutic/instrumentation [MeSH]
lokal Humans [MeSH]
lokal Embolization, Therapeutic/methods [MeSH]
lokal Treatment Outcome [MeSH]
lokal Retrospective Studies [MeSH]
lokal Middle Aged [MeSH]
lokal Intracranial Aneurysm/diagnostic imaging [MeSH]
lokal Original Article
lokal Male [MeSH]
lokal Intracranial aneurysm
lokal Flow-disruption
lokal Equipment Failure Analysis [MeSH]
lokal Propensity Score [MeSH]
lokal Intracranial Aneurysm/therapy [MeSH]
lokal Intrasaccular
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1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-2620-7611|https://frl.publisso.de/adhoc/uri/TGllYmlnLCBUaG9tYXM=|https://frl.publisso.de/adhoc/uri/U2llYmVydCwgRWJlcmhhcmQ=|https://frl.publisso.de/adhoc/uri/Wm9wZnMsIERhdmlk|https://frl.publisso.de/adhoc/uri/UGVubmlnLCBMZW5oYXJk|https://frl.publisso.de/adhoc/uri/U2NobGFtYW5uLCBNYXJj|https://frl.publisso.de/adhoc/uri/UmFkb21pLCBBbGV4YW5kcmE=|https://frl.publisso.de/adhoc/uri/RG9ybiwgRnJhbnppc2th|https://frl.publisso.de/adhoc/uri/S2FiYmFzY2gsIENocmlzdG9waA==
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    1000 Förderer Universitätsklinikum Köln |
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