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1000 Titel
  • Variability in resistance training trajectories of breast cancer patients undergoing therapy
1000 Autor/in
  1. Koeppel, Maximilian |
  2. Steindorf, Karen |
  3. Schmidt, Martina |
  4. Rosenberger, Friederike |
  5. Wiskemann, Joachim |
1000 Verlag
  • Springer Berlin Heidelberg
1000 Erscheinungsjahr 2024
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-12-10
1000 Erschienen in
1000 Quellenangabe
  • 33(1):12
1000 Copyrightjahr
  • 2024
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00520-024-09001-4 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11631991/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title> <jats:sec> <jats:title>Purpose</jats:title> <jats:p>In resistance training (RT), the change in volume-load from training sessions (TS) to TS is an indicator of training progress. Resulting growth trajectories are likely to differ between individuals. Understanding this variation is important for exercise planning in general, but even more for clinical populations. We investigated this variation in breast cancer patients undergoing treatment.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods</jats:title> <jats:p>Data of 69 patients from two randomized controlled trails were investigated. They conducted a 12-week RT program. We fitted a quadratic Bayesian regression model to the baseline standardized volume-load over the course of the intervention. We allowed all parameters to vary both between exercises and between individuals.</jats:p> </jats:sec> <jats:sec> <jats:title>Results</jats:title> <jats:p>We observed a positive linear component of 0.093 (95% uncertainty interval (UI) 0.058 to 0.120) and a negative quadratic component of − 0.002 (95% UI -0.008 to 0.001) for the mean trajectory of the change in volume-load. For the different exercises, we observed a dispersion for both the linear (0.043, 95% UI 0.018 to 0.082) and the quadratic component (0.002, 95% UI &lt; 0.001 to 0.004). Variation between individual appears to be approximately four times larger. We also observed between-exercise variation within individuals. Extrapolation of the regression model indicates training progression stagnates after 20.6 TS (95% UI 14.8 to 44.4).</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusion</jats:title> <jats:p>There is substantial variation in RT response between breast cancer patients undergoing tumor therapy and in-between exercises. The non-linear trajectory indicates that training progression will eventually plateau, demanding periodization and timely modification.</jats:p> </jats:sec> <jats:sec> <jats:title>Trial registration</jats:title> <jats:p>BEATE Study: NCT01106820, Date: April 20, 2010; BEST Study: NCT01468766, Date: November 9, 2011.</jats:p> </jats:sec>
1000 Sacherschließung
lokal Female [MeSH]
lokal Aged [MeSH]
lokal Adult [MeSH]
lokal Resistance Training/methods [MeSH]
lokal Humans [MeSH]
lokal Bayesian statistics
lokal Hierarchical model
lokal Middle Aged [MeSH]
lokal Bayes Theorem [MeSH]
lokal Breast Neoplasms/therapy [MeSH]
lokal Exercise oncology
lokal Adjuvant tumor treatment
lokal Research
lokal Response variability
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0003-0683-8915|https://orcid.org/0000-0001-5215-5651|https://orcid.org/0000-0002-2095-2426|https://orcid.org/0000-0002-4147-2958|https://orcid.org/0000-0002-5971-5436
1000 Hinweis
  • DeepGreen-ID: 797780978bba439fa8a29cac85521081 ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
1000 Label
1000 Förderer
  1. Medizinische Fakultät Heidelberg der Universität Heidelberg |
1000 Fördernummer
  1. -
1000 Förderprogramm
  1. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Medizinische Fakultät Heidelberg der Universität Heidelberg |
    1000 Förderprogramm -
    1000 Fördernummer -
1000 Objektart article
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1000 @id frl:6505830.rdf
1000 Erstellt am 2025-02-06T08:59:37.779+0100
1000 Erstellt von 322
1000 beschreibt frl:6505830
1000 Zuletzt bearbeitet 2025-07-30T16:02:12.547+0200
1000 Objekt bearb. Wed Jul 30 16:02:12 CEST 2025
1000 Vgl. frl:6505830
1000 Oai Id
  1. oai:frl.publisso.de:frl:6505830 |
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