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1000 Titel
  • Evaluation of FRESH scores in predicting outcome and quality of life after aneurysmal subarachnoid haemorrhage in a European patient cohort
1000 Autor/in
  1. Hofmann, Björn |
  2. Gundlach, Evgenia P. |
  3. Fischer, Igor |
  4. Muhammad, Sajjad |
  5. Kram, Rainer |
  6. Beseoglu, Kerim |
  7. Cornelius, Jan F. |
1000 Verlag Springer Vienna
1000 Erscheinungsjahr 2024
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-01-23
1000 Erschienen in
1000 Quellenangabe
  • 166(1):29
1000 Copyrightjahr
  • 2024
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00701-024-05909-2 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10806023/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background</jats:title> <jats:p>Despite aneurysmal subarachnoid haemorrhage (aSAH) patients often experiencing physical and mental disabilities impacting their quality of life (QoL), routine assessment of long-term QoL data and predictive tools are limited. This study evaluates the newly developed “functional recovery expected after subarachnoid haemorrhage” (FRESH) scores with long-term outcomes and QoL in European aSAH patients.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods</jats:title> <jats:p>FRESH, FRESH-cog, and FRESH-quol scores were retrospectively obtained from aSAH patients. Patients were contacted, and the modified Rankin Scale (mRS), extended short form-36 (SF-36), and telephone interview for cognitive status (TICS) were collected and performed. The prognostic and empirical outcomes were compared.</jats:p> </jats:sec> <jats:sec> <jats:title>Results</jats:title> <jats:p>Out of 374 patients, 171 patients (54.1%) completed the SF-36, and 154 patients completed the TICS. The SF-36 analysis showed that 32.7% had below-average physical component summary (PCS) scores, and 39.8% had below-average mental component summary (MCS) scores. There was no significant correlation between the FRESH score and PCS (<jats:italic>p</jats:italic> = 0.09736), MCS (<jats:italic>p</jats:italic> = 0.1796), TICS (<jats:italic>p</jats:italic> = 0.7484), or mRS 10–82 months (average 46 months) post bleeding (<jats:italic>p</jats:italic> = 0.024), respectively. There was also no significant correlation found for “FRESH-cog vs. TICS” (<jats:italic>p</jats:italic> = 0.0311), “FRESH-quol vs. PCS” (<jats:italic>p</jats:italic> = 0.0204), “FRESH-quol vs. MCS” (<jats:italic>p</jats:italic> = 0.1361) and “FRESH-quol vs. TICS” (<jats:italic>p</jats:italic> = 0.1608).</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusions</jats:title> <jats:p>This study found no correlation between FRESH scores and validated QoL tools in a European population of aSAH patients. The study highlights the complexity of reliable long-term QoL prognostication in aSAH patients and emphasises the need for further prospective research to also focus on QoL as an important outcome parameter.</jats:p> </jats:sec>
1000 Sacherschließung
lokal Recovery of Function [MeSH]
lokal Humans [MeSH]
lokal Aneurysmal subarachnoid haemorrhage
lokal Quality of life (QoL)
lokal Subarachnoid Hemorrhage/diagnosis [MeSH]
lokal Retrospective Studies [MeSH]
lokal Subarachnoid Hemorrhage/complications [MeSH]
lokal Original Article
lokal Patient-reported outcome
lokal SF-36
lokal Patients [MeSH]
lokal Quality of Life [MeSH]
lokal Vascular Neurosurgery – Other
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0003-1868-4319|https://frl.publisso.de/adhoc/uri/R3VuZGxhY2gsIEV2Z2VuaWEgUC4=|https://orcid.org/0000-0001-6347-6346|https://orcid.org/0000-0002-6734-7979|https://frl.publisso.de/adhoc/uri/S3JhbSwgUmFpbmVy|https://frl.publisso.de/adhoc/uri/QmVzZW9nbHUsIEtlcmlt|https://frl.publisso.de/adhoc/uri/Q29ybmVsaXVzLCBKYW4gRi4=
1000 Hinweis
  • DeepGreen-ID: 0301b1393ac941b39b65c8ac211ab6e3 ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
1000 Label
1000 Förderer
  1. Universitätsklinikum Düsseldorf. Anstalt öffentlichen Rechts |
1000 Fördernummer
  1. -
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  1. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Universitätsklinikum Düsseldorf. Anstalt öffentlichen Rechts |
    1000 Förderprogramm -
    1000 Fördernummer -
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1000 Erstellt am 2025-07-05T06:37:50.046+0200
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1000 Objekt bearb. Tue Aug 19 12:31:55 CEST 2025
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