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1000 Titel
  • Post-viral symptoms and conditions are more frequent in COVID-19 than influenza, but not more persistent
1000 Autor/in
  1. Tesch, Falko |
  2. Ehm, Franz |
  3. Loser, Friedrich |
  4. Bechmann, Lars |
  5. Vivirito, Annika |
  6. Wende, Danny |
  7. Batram, Manuel |
  8. Buschmann, Tilo |
  9. Menzer, Simone |
  10. Ludwig, Marion |
  11. Roessler, Martin |
  12. Seifert, Martin |
  13. Margolis, Giselle Sarganas |
  14. Reitzle, Lukas |
  15. König, Christina |
  16. Schulte, Claudia |
  17. Hertle, Dagmar |
  18. Ballesteros, Pedro |
  19. Baßler, Stefan |
  20. Bertele, Barbara |
  21. Bitterer, Thomas |
  22. Riederer, Cordula |
  23. Sobik, Franziska |
  24. Scheidt-Nave, Christa |
  25. Schmitt, Jochen |
1000 Verlag BioMed Central
1000 Erscheinungsjahr 2024
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-10-09
1000 Erschienen in
1000 Quellenangabe
  • 24(1):1126
1000 Copyrightjahr
  • 2024
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12879-024-10059-y |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11465902/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>Post-viral symptoms have long been known in the medical community but have received more public attention during the COVID-19 pandemic. Many post-viral symptoms were reported as particularly frequent after SARS-CoV-2 infection. However, there is still a lack of evidence regarding the specificity, frequency and persistence of these symptoms in comparison to other viral infectious diseases such as influenza.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>We investigated a large population-based cohort based on German routine healthcare data. We matched 573,791 individuals with a PCR-test confirmed SARS-CoV-2 infection from the year 2020 to contemporary controls without SARS-CoV-2 infection and controls from the last influenza outbreak in 2018 and followed them up to 18 months.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>We found that post-viral symptoms as defined for COVID-19 by the WHO as well as tissue damage were more frequent among the COVID-19 cohort than the influenza or contemporary control cohort. The persistence of post-viral symptoms was similar between COVID-19 and influenza.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusion</jats:title> <jats:p>Post-viral symptoms following SARS-CoV-2 infection constitute a substantial disease burden as they are frequent and often persist for many months. As COVID-19 is becoming endemic, the disease must not be trivialized. Research should focus on the development of effective treatments for post-viral symptoms.</jats:p> </jats:sec>
1000 Sacherschließung
gnd 1206347392 COVID-19
lokal Adolescent [MeSH]
lokal Female [MeSH]
lokal Aged, 80 and over [MeSH]
lokal Influenza, Human/virology [MeSH]
lokal Cohort study
lokal Aged [MeSH]
lokal Claims data
lokal Adult [MeSH]
lokal Humans [MeSH]
lokal Middle Aged [MeSH]
lokal Post-Acute COVID-19 Syndrome [MeSH]
lokal Germany/epidemiology [MeSH]
lokal Cohort Studies [MeSH]
lokal Long-Term Effects of COVID-19 Infections collection
lokal Post-COVID
lokal Male [MeSH]
lokal Research
lokal Influenza
lokal Young Adult [MeSH]
lokal Influenza, Human/epidemiology [MeSH]
lokal COVID-19/epidemiology [MeSH]
lokal SARS-CoV-2 [MeSH]
lokal SARS-CoV-2
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1000 Liste der Beteiligten
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  1. Technische Universität Dresden |
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    1000 Förderer Technische Universität Dresden |
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