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1000 Titel
  • Early intraocular lens explantations: 10-year database analysis
1000 Autor/in
  1. Friedrich, Maximilian |
  2. Son, Hyeck-Soo |
  3. Hassel, Oliver |
  4. Teich, Lilly |
  5. Augustin, Victor Aristide |
  6. Khoramnia, Ramin |
  7. Auffarth, Gerd Uwe |
  8. Yildirim, Timur Mert |
1000 Verlag BioMed Central
1000 Erscheinungsjahr 2024
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-07-22
1000 Erschienen in
1000 Quellenangabe
  • 24(1):300
1000 Copyrightjahr
  • 2024
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12886-024-03570-y |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11265132/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>The aim of this study was to analyze the causes and characteristics of IOL explantation within the first year after primary implantation.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>In this retrospective, cross sectional database study, a database consisting of over 2500 IOL explants sent from 199 national and international doctors over the past 10 years was analyzed. All IOLs explanted within the first year after implantation were included in this analysis. Explants with insufficient information as well as phakic and Add-on IOLs were excluded. Main outcome measures were the reason for explantation, the time between implantation and explantation, as well as IOLs’ and patients’ characteristics. Additionally, the explanted IOLs were microscopically and histologically analyzed, as required.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>Of all explanted IOLs from the database, 1.9% (<jats:italic>n</jats:italic> = 50) were explanted within the first year after implantation. The most frequent reasons for early IOL explantation were IOL dislocation (32%), visual intolerance (26%), opacification (20%), and intraoperative complications (16%). The time between implantation and explantation was the shortest in cases with intraoperative complications (1.5 ± 3.1 days), followed by IOL dislocation (90.9 ± 103.9 days), visual intolerance (98.3 ± 86.5 days), opacifications (253.5 ± 124.0 days) and other indications (249.7 ± 124.0 days). Calcification of hydrophilic IOLs was the main type of opacification (80%). Notably, seven IOLs required immediate intraoperative exchange due to an intraoperative crack in the optic or a torn off haptic.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusion</jats:title> <jats:p>Indications for early IOL explantation were IOL dislocation, visual intolerance, opacification, and intraoperative complications. Especially intraoperative damages to the IOL and early calcification show a potential for improvement of affected IOLs and implantation systems.</jats:p> </jats:sec>
1000 Sacherschließung
lokal Device Removal [MeSH]
lokal Aged, 80 and over [MeSH]
lokal Aged [MeSH]
lokal Postoperative Complications/epidemiology [MeSH]
lokal Intraoperative Complications/epidemiology [MeSH]
lokal Complication
lokal Databases, Factual [MeSH]
lokal Visual Acuity [MeSH]
lokal Male [MeSH]
lokal Lens Implantation, Intraocular [MeSH]
lokal Surgery
lokal Intraocular lens
lokal Female [MeSH]
lokal Lenses, Intraocular/adverse effects [MeSH]
lokal Adult [MeSH]
lokal Humans [MeSH]
lokal Retrospective Studies [MeSH]
lokal Middle Aged [MeSH]
lokal Cataract
lokal Cross-Sectional Studies [MeSH]
lokal Intraoperative
lokal Prosthesis Failure [MeSH]
lokal Time Factors [MeSH]
lokal Research
lokal IOL exchange
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1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/RnJpZWRyaWNoLCBNYXhpbWlsaWFu|https://frl.publisso.de/adhoc/uri/U29uLCBIeWVjay1Tb28=|https://frl.publisso.de/adhoc/uri/SGFzc2VsLCBPbGl2ZXI=|https://frl.publisso.de/adhoc/uri/VGVpY2gsIExpbGx5|https://frl.publisso.de/adhoc/uri/QXVndXN0aW4sIFZpY3RvciBBcmlzdGlkZQ==|https://frl.publisso.de/adhoc/uri/S2hvcmFtbmlhLCBSYW1pbg==|https://frl.publisso.de/adhoc/uri/QXVmZmFydGgsIEdlcmQgVXdl|https://frl.publisso.de/adhoc/uri/WWlsZGlyaW0sIFRpbXVyIE1lcnQ=
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  1. Medizinische Fakultät Heidelberg der Universität Heidelberg |
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1000 Dateien
  1. Early intraocular lens explantations: 10-year database analysis
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    1000 Förderer Medizinische Fakultät Heidelberg der Universität Heidelberg |
    1000 Förderprogramm -
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1000 Erstellt am 2025-07-05T14:38:30.428+0200
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1000 Zuletzt bearbeitet 2025-08-15T21:17:34.675+0200
1000 Objekt bearb. Fri Aug 15 21:17:34 CEST 2025
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