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1000 Titel
  • Videogame training increases clinical well-being, attention and hippocampal-prefrontal functional connectivity in patients with schizophrenia
1000 Autor/in
  1. Becker, Maxi |
  2. Fischer, Djo |
  3. Kühn, Simone |
  4. Gallinat, Jürgen |
1000 Verlag Nature Publishing Group UK
1000 Erscheinungsjahr 2024
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-05-28
1000 Erschienen in
1000 Quellenangabe
  • 14(1):218
1000 Copyrightjahr
  • 2024
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1038/s41398-024-02945-5 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11133354/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:p>Recent research shows that videogame training enhances neuronal plasticity and cognitive improvements in healthy individuals. As patients with schizophrenia exhibit reduced neuronal plasticity linked to cognitive deficits and symptoms, we investigated whether videogame-related cognitive improvements and plasticity changes extend to this population. In a training study, patients with schizophrenia and healthy controls were randomly assigned to 3D or 2D platformer videogame training or E-book reading (active control) for 8 weeks, 30 min daily. After training, both videogame conditions showed significant increases in sustained attention compared to the control condition, correlated with increased functional connectivity in a hippocampal-prefrontal network. Notably, patients trained with videogames mostly improved in negative symptoms, general psychopathology, and perceived mental health recovery. Videogames, incorporating initiative, goal setting and gratification, offer a training approach closer to real life than current psychiatric treatments. Our results provide initial evidence that they may represent a possible adjunct therapeutic intervention for complex mental disorders.</jats:p>
1000 Sacherschließung
lokal Female [MeSH]
lokal Attention/physiology [MeSH]
lokal Adult [MeSH]
lokal Humans [MeSH]
lokal /631/477/2811
lokal Middle Aged [MeSH]
lokal Neuronal Plasticity/physiology [MeSH]
lokal /692/53/2423
lokal /692/699/476/1799
lokal /9/10
lokal Magnetic Resonance Imaging [MeSH]
lokal Article
lokal Male [MeSH]
lokal Schizophrenic Psychology [MeSH]
lokal Prefrontal Cortex/physiopathology [MeSH]
lokal Video Games [MeSH]
lokal Hippocampus/physiopathology [MeSH]
lokal Schizophrenia/rehabilitation [MeSH]
lokal Schizophrenia/physiopathology [MeSH]
lokal article
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/QmVja2VyLCBNYXhp|https://orcid.org/0000-0002-6248-8748|https://frl.publisso.de/adhoc/uri/S8O8aG4sIFNpbW9uZQ==|https://frl.publisso.de/adhoc/uri/R2FsbGluYXQsIErDvHJnZW4=
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  • DeepGreen-ID: 04055554fc9a49a8af22fa25303f05d5 ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
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1000 @id frl:6519345.rdf
1000 Erstellt am 2025-07-05T17:18:12.513+0200
1000 Erstellt von 322
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1000 Zuletzt bearbeitet 2025-08-14T08:13:50.805+0200
1000 Objekt bearb. Thu Aug 14 08:13:50 CEST 2025
1000 Vgl. frl:6519345
1000 Oai Id
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