Brief communication: coagulation profiles of HIV positive patients on antiretroviral therapy (ART) at the Mampong Municipal Hospital, Ashanti-Region, Ghana: a case control study

  1. Opoku, Freddie Boateng
  2. Yalley, Akua Koaso
  3. Nii-Trebi, Nicholas Israel
  4. Ahlin, Ekoutiame
  5. Yalley, Abena Asefuaba
  6. Kyeremeh, Ransford

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1000 Titel
  • Brief communication: coagulation profiles of HIV positive patients on antiretroviral therapy (ART) at the Mampong Municipal Hospital, Ashanti-Region, Ghana: a case control study
1000 Autor/in
  1. Opoku, Freddie Boateng |
  2. Yalley, Akua Koaso |
  3. Nii-Trebi, Nicholas Israel |
  4. Ahlin, Ekoutiame |
  5. Yalley, Abena Asefuaba |
  6. Kyeremeh, Ransford |
1000 Verlag BioMed Central
1000 Erscheinungsjahr 2024
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-10-22
1000 Erschienen in
1000 Quellenangabe
  • 21(1):72
1000 Copyrightjahr
  • 2024
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12981-024-00665-w |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11494772/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • This study aimed to ascertain how the current two ART regimens used in Ghana affected HIV patients' coagulation profiles. A case-control study was conducted on 102 HIV positive patients at the Mampong Municipal Hospital. Coagulation parameters measured showed APTT was normal in majority of ART-experienced participants but prolonged in majority of ART-naïve participants. The mean platelet count was significantly higher in ART-experienced participants. No significant differences were found between the coagulation profiles of ART-experienced patients on two different drug regimens. In conclusion, current ART can enhance the coagulation profiles in HIV-infected patients, by improving platelet count and APTT.
1000 Sacherschließung
lokal Activated partial thromboplastin time
lokal Female [MeSH]
lokal Adult [MeSH]
lokal Partial Thromboplastin Time [MeSH]
lokal Humans [MeSH]
lokal HIV Infections/blood [MeSH]
lokal International normalized ratio
lokal Coagulation profile
lokal Antiretroviral therapy
lokal Hospitals, Municipal [MeSH]
lokal Anti-HIV Agents/therapeutic use [MeSH]
lokal Middle Aged [MeSH]
lokal Platelet Count [MeSH]
lokal Human immunodeficiency virus
lokal Ghana/epidemiology [MeSH]
lokal Platelet count
lokal Male [MeSH]
lokal HIV Infections/drug therapy [MeSH]
lokal Research
lokal Young Adult [MeSH]
lokal Case-Control Studies [MeSH]
lokal Blood Coagulation/drug effects [MeSH]
lokal Antiretroviral Therapy, Highly Active [MeSH]
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/T3Bva3UsIEZyZWRkaWUgQm9hdGVuZw==|https://frl.publisso.de/adhoc/uri/WWFsbGV5LCBBa3VhIEtvYXNv|https://frl.publisso.de/adhoc/uri/TmlpLVRyZWJpLCBOaWNob2xhcyBJc3JhZWw=|https://frl.publisso.de/adhoc/uri/QWhsaW4sIEVrb3V0aWFtZQ==|https://frl.publisso.de/adhoc/uri/WWFsbGV5LCBBYmVuYSBBc2VmdWFiYQ==|https://frl.publisso.de/adhoc/uri/S3llcmVtZWgsIFJhbnNmb3Jk
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1000 Erstellt am 2025-07-05T17:59:42.503+0200
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1000 Zuletzt bearbeitet 2025-08-11T10:55:00.425+0200
1000 Objekt bearb. Mon Aug 11 10:55:00 CEST 2025
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