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1000 Titel
  • Telemedicine-based antibiotic stewardship program in pediatrics: study protocol of a stepped wedge cluster randomized trial—the TeleKasper study
1000 Autor/in
  1. Diexer, Sophie |
  2. Ihling, Angelika |
  3. Gomes, Delphina |
  4. Moritz, Stefan |
  5. Simon, Arne |
  6. Dohna-Schwake, Christian |
  7. Mikolajczyk, Rafael |
  8. Huebner, Johannes |
  9. von Both, Ulrich |
  10. the TeleKasper Consortium |
1000 Verlag BioMed Central
1000 Erscheinungsjahr 2024
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-10-14
1000 Erschienen in
1000 Quellenangabe
  • 25(1):678
1000 Copyrightjahr
  • 2024
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s13063-024-08493-z |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11476715/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract </jats:title><jats:sec> <jats:title>Background </jats:title> <jats:p>Overuse and misuse of antibiotics is one of the driving factors of antimicrobial resistance, a growing global health threat. The use of antibiotics is particularly high in children. Even though the implementation of antibiotic stewardship programs (ASP) in pediatrics has been shown to reduce antibiotic use, this implementation has been limited to large university hospitals in Germany. Telemedicine applications might be an effective approach to implement ASP in non-university settings.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>This protocol details the TeleKasper study (Telemedical Competence Network “Antibiotic Stewardship in Pediatrics”). Tele-Kasper is a stepped-wedge cluster-randomized trial that will be conducted across non-university children’s hospitals in Germany. The intervention consists of a telemedical consultation service in the form of a network in different German areas, using an app as a communication tool. The primary outcome will be a 20% reduction in overall antibiotic consumption measured using defined daily doses per 100 patient days.</jats:p> </jats:sec><jats:sec> <jats:title>Discussion</jats:title> <jats:p>The TeleKasper study aims to implement and evaluate a prototype for a nationwide antibiotic stewardship program by telemedical means in pediatric departments in non-university hospitals in Germany to promote rational antibiotic use and improve medical care for infections.</jats:p> </jats:sec><jats:sec> <jats:title>Trial registration</jats:title> <jats:p>German Clinical Trials Register (DRKS) DRKS00028534. Registered on 22nd of April 2022.</jats:p> </jats:sec>
1000 Sacherschließung
lokal Antimicrobial Stewardship/methods [MeSH]
lokal Telemedicine [MeSH]
lokal Pediatrics
lokal Pediatrics/standards [MeSH]
lokal Anti-Bacterial Agents/therapeutic use [MeSH]
lokal Randomized controlled trial
lokal Study Protocol
lokal Humans [MeSH]
lokal Hospitals, Pediatric [MeSH]
lokal Multicenter Studies as Topic [MeSH]
lokal Antimicrobial stewardship
lokal Randomized Controlled Trials as Topic [MeSH]
lokal Telemedicine
lokal Germany [MeSH]
lokal Practice Patterns, Physicians'/standards [MeSH]
lokal Child [MeSH]
lokal Child, Preschool [MeSH]
lokal Pediatrics/methods [MeSH]
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/RGlleGVyLCBTb3BoaWU=|https://frl.publisso.de/adhoc/uri/SWhsaW5nLCBBbmdlbGlrYQ==|https://frl.publisso.de/adhoc/uri/R29tZXMsIERlbHBoaW5h|https://frl.publisso.de/adhoc/uri/TW9yaXR6LCBTdGVmYW4=|https://frl.publisso.de/adhoc/uri/U2ltb24sIEFybmU=|https://frl.publisso.de/adhoc/uri/RG9obmEtU2Nod2FrZSwgQ2hyaXN0aWFu|https://frl.publisso.de/adhoc/uri/TWlrb2xhamN6eWssIFJhZmFlbA==|https://frl.publisso.de/adhoc/uri/SHVlYm5lciwgSm9oYW5uZXM=|https://frl.publisso.de/adhoc/uri/dm9uIEJvdGgsIFVscmljaA==|https://frl.publisso.de/adhoc/uri/dGhlIFRlbGVLYXNwZXIgQ29uc29ydGl1bQ==
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    1000 Förderer Klinikum der Universität München |
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