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1000 Titel
  • Longterm course of neuropsychological symptoms and ME/CFS after SARS-CoV-2-infection: a prospective registry study
1000 Autor/in
  1. Reuken, Philipp A. |
  2. Besteher, Bianca |
  3. Kathrin, Finke |
  4. Fischer, A. |
  5. Holl, A. |
  6. Katzer, Katrin |
  7. Lehmann-Pohl, K. |
  8. Lemhöfer, Christina |
  9. Nowka, M. |
  10. Puta, Christian |
  11. Walter, M. |
  12. Weissenborn, Christian |
  13. Stallmach, Andreas |
1000 Verlag Springer Berlin Heidelberg
1000 Erscheinungsjahr 2023
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2023-08-16
1000 Erschienen in
1000 Quellenangabe
  • 274(8):1903-1910
1000 Copyrightjahr
  • 2023
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00406-023-01661-3 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11579079/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:p>A significant proportion of patients after SARS-CoV-2 infection suffer from long-lasting symptoms. Although many different symptoms are described, the majority of patients complains about neuropsychological symptoms. Additionally, a subgroup of patients fulfills diagnostic criteria for ME/CFS. We analyzed a registry of all patients presenting in the out-patients clinic at a German university center. For patients with more than one visit, changes in reported symptoms from first to second visit were analyzed. A total of 1022 patients were included in the study, 411 of them had more than one visit. 95.5% of the patients reported a polysymptomatic disease. At the first visit 31.3% of the patients fulfilled ME/CFS criteria after a median time of 255 days post infection and and at the second visit after a median of 402 days, 19.4% still suffered from ME/CFS. Self-reported fatigue (83.7–72.7%) and concentration impairment (66.2–57.9%) decreased from first to second visit contrasting non-significant changes in the structured screening. A significant proportion of SARS-CoV-2 survivors presenting with ongoing symptoms present with ME/CFS. Although the proportion of subjective reported symptoms and their severity reduce over time, a significant proportion of patients suffer from long-lasting symptoms necessitating new therapeutic concepts.</jats:p>
1000 Sacherschließung
gnd 1206347392 COVID-19
lokal Female [MeSH]
lokal SARS-CoV2
lokal Aged [MeSH]
lokal ME/CFS
lokal Adult [MeSH]
lokal Humans [MeSH]
lokal Prospective Studies [MeSH]
lokal COVID-19/psychology [MeSH]
lokal Middle Aged [MeSH]
lokal Fatigue/etiology [MeSH]
lokal Post-Acute COVID-19 Syndrome [MeSH]
lokal COVID-19/complications [MeSH]
lokal Germany/epidemiology [MeSH]
lokal Long-COVID
lokal Post-COVID
lokal Male [MeSH]
lokal Fatigue
lokal Original Paper
lokal SARS-CoV-2 [MeSH]
lokal Registries [MeSH]
lokal Neuropsychological Tests [MeSH]
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-7696-475X|https://orcid.org/0000-0001-7989-9298|https://orcid.org/0000-0001-8546-7141|https://frl.publisso.de/adhoc/uri/RmlzY2hlciwgQS4=|https://frl.publisso.de/adhoc/uri/SG9sbCwgQS4=|https://orcid.org/0000-0003-1136-0784|https://frl.publisso.de/adhoc/uri/TGVobWFubi1Qb2hsLCBLLg==|https://orcid.org/0000-0002-6206-4064|https://frl.publisso.de/adhoc/uri/Tm93a2EsIE0u|https://orcid.org/0000-0003-3936-4605|https://frl.publisso.de/adhoc/uri/V2FsdGVyLCBNLg==|https://orcid.org/0009-0008-6378-1875|https://orcid.org/0000-0002-6101-5244
1000 Hinweis
  • DeepGreen-ID: 52df5a83caa543e8b140b0cccd139af1 ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
1000 Label
1000 Förderer
  1. Thüringer Aufbaubank |
  2. Friedrich-Schiller-Universität Jena |
1000 Fördernummer
  1. -
  2. -
1000 Förderprogramm
  1. -
  2. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Thüringer Aufbaubank |
    1000 Förderprogramm -
    1000 Fördernummer -
  2. 1000 joinedFunding-child
    1000 Förderer Friedrich-Schiller-Universität Jena |
    1000 Förderprogramm -
    1000 Fördernummer -
1000 Objektart article
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1000 @id frl:6519615.rdf
1000 Erstellt am 2025-07-05T19:07:09.384+0200
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1000 Zuletzt bearbeitet 2025-08-14T07:38:05.637+0200
1000 Objekt bearb. Thu Aug 14 07:38:05 CEST 2025
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1000 Oai Id
  1. oai:frl.publisso.de:frl:6519615 |
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