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1000 Titel
  • Sensory nerve conduction stimulus threshold measurements of the infraorbital nerve and its applicability as a diagnostic tool in horses with trigeminal-mediated headshaking
1000 Autor/in
  1. Nessler, Jasmin Nicole |
  2. Delarocque, Julien |
  3. Kloock, Tanja |
  4. Twele, Lara |
  5. Neudeck, Stephan |
  6. Meyerhoff, Nina |
  7. Riese, Franziska |
  8. Cavalleri, Jessica-M. V. |
  9. Tipold, Andrea |
  10. Feige, Karsten |
  11. Niebuhr, Tobias |
1000 Verlag BioMed Central
1000 Erscheinungsjahr 2024
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-05-16
1000 Erschienen in
1000 Quellenangabe
  • 20(1):201
1000 Copyrightjahr
  • 2024
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12917-024-04068-x |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11097574/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>To determine whether sensory nerve conduction stimulus threshold measurements of the infraorbital nerve are able to differentiate horses with idiopathic trigeminal-mediated headshaking (i-TMHS) from healthy horses and from horses with secondary trigeminal-mediated headshaking (s-TMHS). In a prospective trial, headshaking horses were examined using a standardized diagnostic protocol, including advanced diagnostics such as computed tomography and 3-Tesla-magnetic resonance imaging (MRI), to differentiate s-TMHS from i-TMHS. Clinically healthy horses served as controls. Within this process, patients underwent general anesthesia, and the minimal sensory nerve conduction stimulus threshold (SNCT) of the infraorbital nerve was measured using a bipolar concentric needle electrode. Sensory nerve action potentials (SNAP) were assessed in 2.5–5 mA intervals. Minimal SNCT as well as additional measurements were calculated.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>In 60 horses, SNAP could be recorded, of which 43 horses had i-TMHS, six had suspected s-TMHS, three horses had non-facial headshaking, and eight healthy horses served as controls. Controls had a minimal SNCT ≥ 15 mA, whereas 14/43 horses with i-TMHS and 2/6 horses with s-TMHS showed a minimal SNCT ≤ 10 mA. Minimal SNCT ≤ 10 mA showed 100% specificity to distinguish TMHS from controls, but the sensitivity was only 41%.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusion</jats:title> <jats:p>A minimal SNCT of the infraorbital nerve ≤ 10 mA was able to differentiate healthy horses from horses with TMHS. Nevertheless, a higher minimal SNCT did not exclude i-TMHS or s-TMHS and minimal SNCT does not distinguish s-TMHS from i-TMHS.</jats:p> </jats:sec>
1000 Sacherschließung
lokal Female [MeSH]
lokal Horse Diseases/diagnosis [MeSH]
lokal Prospective Studies [MeSH]
lokal Trigeminal Nerve/physiology [MeSH]
lokal Trigeminal-mediated head shaking
lokal Horses [MeSH]
lokal Animals [MeSH]
lokal Infraorbital nerve
lokal Male [MeSH]
lokal Neuropathy
lokal Sensory nerve conduction stimulus threshold
lokal Research
lokal Neural Conduction/physiology [MeSH]
lokal Head [MeSH]
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1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/TmVzc2xlciwgSmFzbWluIE5pY29sZQ==|https://frl.publisso.de/adhoc/uri/RGVsYXJvY3F1ZSwgSnVsaWVu|https://frl.publisso.de/adhoc/uri/S2xvb2NrLCBUYW5qYQ==|https://frl.publisso.de/adhoc/uri/VHdlbGUsIExhcmE=|https://frl.publisso.de/adhoc/uri/TmV1ZGVjaywgU3RlcGhhbg==|https://frl.publisso.de/adhoc/uri/TWV5ZXJob2ZmLCBOaW5h|https://frl.publisso.de/adhoc/uri/Umllc2UsIEZyYW56aXNrYQ==|https://frl.publisso.de/adhoc/uri/Q2F2YWxsZXJpLCBKZXNzaWNhLU0uIFYu|https://frl.publisso.de/adhoc/uri/VGlwb2xkLCBBbmRyZWE=|https://frl.publisso.de/adhoc/uri/RmVpZ2UsIEthcnN0ZW4=|https://frl.publisso.de/adhoc/uri/TmllYnVociwgVG9iaWFz
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  1. Stiftung Tierärztliche Hochschule Hannover (TIHO) |
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    1000 Förderer Stiftung Tierärztliche Hochschule Hannover (TIHO) |
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