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1000 Titel
  • Forensic age estimation by MRI of the knee – comparison of two classifications for ossification stages in a German population
1000 Autor/in
  1. Malokaj, V |
  2. MF, Wernsing |
  3. SN, Kunz |
  4. Beer, M |
  5. Vogele, Daniel |
1000 Verlag Springer Berlin Heidelberg
1000 Erscheinungsjahr 2024
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-07-04
1000 Erschienen in
1000 Quellenangabe
  • 138(6):2387-2400
1000 Copyrightjahr
  • 2024
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00414-024-03281-5 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11490462/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:sec> <jats:title>Aim and objectives</jats:title> <jats:p>In forensic age estimation e.g. for judicial proceedings surpassed age thresholds can be legally relevant. To examine age related differences in skeletal development the recommendations by the Study Group on Forensic Age Diagnostics (AGFAD) are based on ionizing radiation (among others orthopantomograms, plain x-rays of the hand). Vieth et al. and Ottow et al. proposed MRI-classifications for the epiphyseal-diaphyseal fusion of the knee joint to define different age groups in healthy volunteers. The aim of the present study was to directly compare these two classifications in a large German patient population.</jats:p> </jats:sec><jats:sec> <jats:title>Materials and methods</jats:title> <jats:p>MRI of the knee joint of 900 patients (405 female, 495 male) from 10 to 28 years of age were retrospectively analyzed. Acquired T1-weighted turbo spin-echo sequence (TSE) and T2-weighted sequence with fat suppression by turbo inversion recovery magnitude (TIRM) were analyzed for the two classifications. The different bony fusion stages of the two classifications were determined and the corresponding chronological ages assigned. Differences between the sexes were analyzed. Intra- and inter-observer agreements were determined using Cohen’s kappa.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>With the classification of Ottow et al. it was possible to determine completion of the 18th and 21st year of life in both sexes. With the classification of Vieth et al. completion of the 18th year of life for female patients and the 14th and 21st year of life in both sexes could be determined. The intra- and inter-observer agreement levels were very good (κ &gt; 0.82).</jats:p> </jats:sec><jats:sec> <jats:title>Conclusion</jats:title> <jats:p>In the large German patient cohort of this study it was possible to determine the 18th year of life with for both sexes with the classification of Ottow et al. and for female patients with the classification of Vieth et al. It was also possible to determine the 21st year of life for all bones with the classification of Ottow et al. and for the distal femur with the classification of Vieth et al.</jats:p> </jats:sec>
1000 Sacherschließung
lokal Adolescent [MeSH]
lokal Female [MeSH]
lokal Osteogenesis [MeSH]
lokal Knee Joint/diagnostic imaging [MeSH]
lokal Adult [MeSH]
lokal Forensic age estimation
lokal Humans [MeSH]
lokal Epiphyses/diagnostic imaging [MeSH]
lokal Retrospective Studies [MeSH]
lokal Bone age
lokal Original Article
lokal Knee MRI
lokal Magnetic Resonance Imaging [MeSH]
lokal Male [MeSH]
lokal Germany [MeSH]
lokal Young Adult [MeSH]
lokal Ossification stages
lokal Age Determination by Skeleton/methods [MeSH]
lokal Epiphyses/growth
lokal Child [MeSH]
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/TWFsb2thaiwgVg==|https://frl.publisso.de/adhoc/uri/TUYsIFdlcm5zaW5n|https://frl.publisso.de/adhoc/uri/U04sIEt1bno=|https://frl.publisso.de/adhoc/uri/QmVlciwgTQ==|https://orcid.org/0000-0002-6421-1400
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  1. Universitätsklinikum Ulm |
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    1000 Förderer Universitätsklinikum Ulm |
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