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1000 Titel
  • Early extubation after elective surgical aortic valve replacement during the COVID-19 pandemic
1000 Autor/in
  1. Fischbach, Anna |
  2. Simons, Julia Alexandra |
  3. Wiegand, Steffen B. |
  4. Ammon, Lieselotte |
  5. Kopp, Rüdger |
  6. Marx, Gernot |
  7. Rossaint, Rolf |
  8. Akhyari, Payam |
  9. Schälte, Gereon |
1000 Verlag BioMed Central
1000 Erscheinungsjahr 2024
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-08-24
1000 Erschienen in
1000 Quellenangabe
  • 19(1):490
1000 Copyrightjahr
  • 2024
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s13019-024-02989-0 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11344404/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>Surgical aortic valve replacement (SAVR) is an established therapy for severe calcific aortic stenosis. Enhanced recovery after cardiac surgery (ERACS) protocols have been shown to improve outcomes for elective cardiac procedures. The COVID-19 pandemic prompted early extubation post-elective surgeries to preserve critical care resources.</jats:p> </jats:sec><jats:sec> <jats:title>Aim of this study</jats:title> <jats:p>To investigate the effects of extubating patients within 6 h post-elective SAVR on hospital and ICU length of stay, mortality rates, ICU readmissions, and postoperative pneumonia.</jats:p> </jats:sec><jats:sec> <jats:title>Study Design and methods</jats:title> <jats:p>The retrospective analysis at the University Hospital Aachen, Germany, includes data from 2017 to 2022 and compares a total of 73 elective SAVR patients. Among these, 23 patients were extubated within 6 h (EXT group), while 50 patients remained intubated for over 6 h (INT group).</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>The INT group experienced longer postoperative ventilation, needed more vasopressor support, had a higher incidence of postoperative pneumonia, and longer ICU length of stay. No significant differences were noted in overall hospital length of stay, mortality, or ICU readmission rates between the groups.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusion</jats:title> <jats:p>This study demonstrates that early extubation in high-risk, multimorbid surgical aortic valve replacement patients is safe, and is associated with a reduction of pneumonia rates, and with shorter ICU and hospital length of stays, reinforcing the benefits of ERACS protocols, especially critical during the COVID-19 pandemic to optimize intensive care use.</jats:p> </jats:sec>
1000 Sacherschließung
gnd 1206347392 COVID-19
lokal Length of Stay/statistics
lokal Aged, 80 and over [MeSH]
lokal Aged [MeSH]
lokal Enhanced recovery after cardiac surgery
lokal Aortic Valve/surgery [MeSH]
lokal Postoperative Complications/epidemiology [MeSH]
lokal Germany/epidemiology [MeSH]
lokal Male [MeSH]
lokal ERACS
lokal Early extubation
lokal Aortic Valve Stenosis/surgery [MeSH]
lokal COVID-19/epidemiology [MeSH]
lokal Aortic valve surgery
lokal SARS-CoV-2 [MeSH]
lokal Heart Valve Prosthesis Implantation/methods [MeSH]
lokal Female [MeSH]
lokal Humans [MeSH]
lokal Airway Extubation [MeSH]
lokal Retrospective Studies [MeSH]
lokal Elective Surgical Procedures [MeSH]
lokal Middle Aged [MeSH]
lokal Surgical aortic valve replacement
lokal Pandemics [MeSH]
lokal COVID-19/prevention
lokal Research
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/RmlzY2hiYWNoLCBBbm5h|https://frl.publisso.de/adhoc/uri/U2ltb25zLCBKdWxpYSBBbGV4YW5kcmE=|https://frl.publisso.de/adhoc/uri/V2llZ2FuZCwgU3RlZmZlbiBCLg==|https://frl.publisso.de/adhoc/uri/QW1tb24sIExpZXNlbG90dGU=|https://frl.publisso.de/adhoc/uri/S29wcCwgUsO8ZGdlcg==|https://frl.publisso.de/adhoc/uri/TWFyeCwgR2Vybm90|https://frl.publisso.de/adhoc/uri/Um9zc2FpbnQsIFJvbGY=|https://frl.publisso.de/adhoc/uri/QWtoeWFyaSwgUGF5YW0=|https://frl.publisso.de/adhoc/uri/U2Now6RsdGUsIEdlcmVvbg==
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1000 Förderer
  1. Universitätsklinikum RWTH Aachen |
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    1000 Förderer Universitätsklinikum RWTH Aachen |
    1000 Förderprogramm -
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1000 Erstellt am 2025-07-06T11:12:19.159+0200
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1000 Zuletzt bearbeitet 2025-08-04T08:46:04.536+0200
1000 Objekt bearb. Mon Aug 04 08:46:04 CEST 2025
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