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1000 Titel
  • The relation of osteoporotic vertebral fractures and spine degeneration on the occurrence of complications: a systematic review
1000 Autor/in
  1. Wiersbicki, Dina W. |
  2. Osterhoff, Georg |
  3. Heyde, Christoph-E |
  4. Pieroh, Philipp |
1000 Verlag
  • Springer Berlin Heidelberg
1000 Erscheinungsjahr 2024
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-07-17
1000 Erschienen in
1000 Quellenangabe
  • 33(8):3213-3220
1000 Copyrightjahr
  • 2024
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00586-024-08403-6 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:sec> <jats:title>Study design</jats:title> <jats:p>Systematic review.</jats:p> </jats:sec><jats:sec> <jats:title>Purpose</jats:title> <jats:p>Osteoporotic vertebral fractures (OVFs) and degenerative spine conditions are age-related and associated with higher morbidity and mortality and greater health care costs. The relationship between OVFs and prevalent spine degeneration is rarely reported. The aim of this study was to systematically review current literature on the influence of preexisting degenerative spine conditions in patients with OVFs on the occurrence of complications during and after treatment.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>A systematic literature review adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines was performed using Web of Science and MEDLINE. We considered English and German articles published from January 1990 to December 2022. The inclusion criteria were patients with OVFs and preexisting spinal degeneration with complications such as subsequent fractures, deformity, implant failure and surgical and general complications. The included studies were controlled trials, cohort studies, and case series.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>Ten articles met the inclusion criteria (two prospective studies, seven retrospective studies and one case series). These were divided into two groups: studies on OVFs in patients with coexisting degenerative spine conditions (<jats:italic>n</jats:italic> = 5) and studies on OVFs following surgical treatment for degenerative spine conditions (<jats:italic>n</jats:italic> = 5). Three studies reported more complications in patients with OVFs and severe degeneration. One study stated the opposite. One study did not find any correlation. The remaining studies described complications narratively. Subsequent fractures were the most frequent complications.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusion</jats:title> <jats:p>OVFs in patients with preexisting spinal degeneration seem to cause more complications. In addition to subsequent fractures, other complications have rarely been examined. The presence of degenerative changes or undergoing surgical correction may increase the risk of subsequent fractures.</jats:p> </jats:sec>
1000 Sacherschließung
lokal Osteoporotic fracture
lokal Spinal Fractures/epidemiology [MeSH]
lokal Spinal degeneration
lokal Humans [MeSH]
lokal Review Article
lokal Postoperative Complications/epidemiology [MeSH]
lokal Osteoporosis
lokal Osteoporotic Fractures/surgery [MeSH]
lokal Spinal Fractures/etiology [MeSH]
lokal Osteoporotic Fractures/epidemiology [MeSH]
lokal Postoperative Complications/etiology [MeSH]
lokal Spinal Fractures/surgery [MeSH]
lokal Vertebral fracture
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1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/V2llcnNiaWNraSwgRGluYSBXLg==|https://frl.publisso.de/adhoc/uri/T3N0ZXJob2ZmLCBHZW9yZw==|https://frl.publisso.de/adhoc/uri/SGV5ZGUsIENocmlzdG9waC1F|https://frl.publisso.de/adhoc/uri/UGllcm9oLCBQaGlsaXBw
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  1. Universitätsklinikum Leipzig |
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    1000 Förderer Universitätsklinikum Leipzig |
    1000 Förderprogramm -
    1000 Fördernummer -
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