Medium-term and peri-lockdown course of psychosocial burden during the ongoing COVID-19 pandemic: a longitudinal study on patients with pre-existing mental disorders

  1. Bartels, Claudia ORCID logo
  2. Hessmann, Philipp
  3. Schmidt, Ulrike
  4. Vogelgsang, Jonathan
  5. Ruhleder, Mirjana
  6. Kratzenberg, Alexander
  7. Treptow, Marit
  8. Reh-Bergen, Thorgund
  9. Abdel-Hamid, Mona
  10. Heß, Luisa
  11. Meiser, Miriam
  12. Signerski-Krieger, Jörg
  13. Radenbach, Katrin
  14. Trost, Sarah
  15. Schott, Björn ORCID logo
  16. Wiltfang, Jens
  17. Wolff-Menzler, Claus
  18. Belz, Michael

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1000 Titel
  • Medium-term and peri-lockdown course of psychosocial burden during the ongoing COVID-19 pandemic: a longitudinal study on patients with pre-existing mental disorders
1000 Autor/in
  1. Bartels, Claudia |
  2. Hessmann, Philipp |
  3. Schmidt, Ulrike |
  4. Vogelgsang, Jonathan |
  5. Ruhleder, Mirjana |
  6. Kratzenberg, Alexander |
  7. Treptow, Marit |
  8. Reh-Bergen, Thorgund |
  9. Abdel-Hamid, Mona |
  10. Heß, Luisa |
  11. Meiser, Miriam |
  12. Signerski-Krieger, Jörg |
  13. Radenbach, Katrin |
  14. Trost, Sarah |
  15. Schott, Björn |
  16. Wiltfang, Jens |
  17. Wolff-Menzler, Claus |
  18. Belz, Michael |
1000 Erscheinungsjahr 2021
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-11-25
1000 Erschienen in
1000 Quellenangabe
  • 272(5):757-771
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00406-021-01351-y |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614217/ |
1000 Ergänzendes Material
  • https://link.springer.com/article/10.1007/s00406-021-01351-y#Sec24 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • While the COVID-19 pandemic continues, patients with pre-existing mental disorders are increasingly recognized as a risk group for adverse outcomes. However, data are conflicting and cover only short time spans so far. Here, we investigate the medium-term and peri-lockdown-related changes of mental health outcomes in such patients in a longitudinal study. A cohort of 159 patients comprising all major mental disorders (ICD-10 F0-F9) were interviewed twice with the Goettingen psychosocial Burden and Symptom Inventory (Goe-BSI) to evaluate psychosocial burden, psychiatric symptoms and resilience at the end of the first (April/May 2020) and the second lockdown in Germany (November/December 2020). For the primary outcome "psychosocial burden" ratings also comprised retrospective pre-pandemic (early 2020) and very early states during the pandemic (March 2020). For all diagnostic groups, psychosocial burden varied significantly over time (p < 0.001) with an increase from the pre-pandemic to the initial phase (p < 0.001), followed by a steady decrease across both lockdowns, normalizing in November/December 2020. Female gender, high adjustment disorder symptom load at baseline and psychiatric comorbidities were risk factors for higher levels and an unfavorable course of psychosocial burden. Most psychiatric symptoms changed minimally, while resilience decreased over time (p = 0.044 and p = 0.037). The longitudinal course of psychosocial burden indicates an initial stress response, followed by a return to pre-pandemic levels even under recurrent lockdown conditions, mimicking symptoms of an adjustment disorder. Strategies for proactive, specific and continuous treatment have to address resilience capacities before their depletion in the pandemic aftermath, especially for patients with additional risk factors.
1000 Sacherschließung
lokal Mental health
lokal Adjustment disorder
lokal Psychosocial stress
lokal SARS-CoV-2
lokal Coronavirus
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0003-3023-9971|https://frl.publisso.de/adhoc/uri/SGVzc21hbm4sIFBoaWxpcHA=|https://frl.publisso.de/adhoc/uri/U2NobWlkdCwgVWxyaWtl|https://frl.publisso.de/adhoc/uri/Vm9nZWxnc2FuZywgSm9uYXRoYW4=|https://frl.publisso.de/adhoc/uri/UnVobGVkZXIsIE1pcmphbmE=|https://frl.publisso.de/adhoc/uri/S3JhdHplbmJlcmcsIEFsZXhhbmRlcg==|https://frl.publisso.de/adhoc/uri/VHJlcHRvdywgTWFyaXQ=|https://frl.publisso.de/adhoc/uri/UmVoLUJlcmdlbiwgVGhvcmd1bmQ=|https://frl.publisso.de/adhoc/uri/QWJkZWwtSGFtaWQsIE1vbmE=|https://frl.publisso.de/adhoc/uri/SGXDnywgTHVpc2E=|https://frl.publisso.de/adhoc/uri/TWVpc2VyLCBNaXJpYW0=|https://frl.publisso.de/adhoc/uri/U2lnbmVyc2tpLUtyaWVnZXIsIErDtnJn|https://frl.publisso.de/adhoc/uri/UmFkZW5iYWNoLCBLYXRyaW4=|https://frl.publisso.de/adhoc/uri/VHJvc3QsIFNhcmFo|https://orcid.org/0000-0002-8237-4481|https://frl.publisso.de/adhoc/uri/V2lsdGZhbmcsIEplbnM=|https://frl.publisso.de/adhoc/uri/V29sZmYtTWVuemxlciwgQ2xhdXM=|https://frl.publisso.de/adhoc/uri/QmVseiwgTWljaGFlbA==
1000 Label
1000 Förderer
  1. Projekt DEAL |
  2. Bundesministerium für Bildung und Forschung |
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  1. Open Access Funding
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1000 Dateien
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    1000 Förderer Projekt DEAL |
    1000 Förderprogramm Open Access Funding
    1000 Fördernummer -
  2. 1000 joinedFunding-child
    1000 Förderer Bundesministerium für Bildung und Forschung |
    1000 Förderprogramm -
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1000 Objektart article
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1000 Erstellt am 2022-07-19T11:34:31.812+0200
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