Prevalence and risk factors of post-COVID-19 condition in adults and children at 6 and 12 months after hospital discharge: a prospective, cohort study in Moscow (StopCOVID)

  1. Pazukhina, Ekaterina
  2. Andreeva, Margarita
  3. Spiridonova, Ekaterina
  4. Bobkova, Polina
  5. Shikhaleva, Anastasia
  6. El-Taravi, Yasmin
  7. Rumyantsev, Mikhail
  8. Gamirova, Aysylu
  9. Bairashevskaia, Anastasiia
  10. Petrova, Polina
  11. Baimukhambetova, Dina
  12. Pikuza, Maria
  13. Abdeeva, Elina
  14. Filippova, Yulia
  15. Deunezhewa, Salima
  16. Nekliudov, Nikita
  17. Bugaeva, Polina
  18. Bulanov, Nikolay
  19. Avdeev, Sergey
  20. Kapustina, Valentina
  21. Guekht, Alla
  22. DunnGalvin, Audrey
  23. Comberiati, Pasquale
  24. Peroni, Diego G.
  25. Apfelbacher, Christian
  26. Genuneit, Jon
  27. Reyes, Luis Felipe
  28. Brackel, Caroline L. H.
  29. Fomin, Victor
  30. Svistunov, Andrey A.
  31. Timashev, Peter
  32. Mazankova, Lyudmila
  33. Miroshina, Alexandra
  34. Samitova, Elmira
  35. Borzakova, Svetlana
  36. Bondarenko, Elena
  37. Korsunskiy, Anatoliy A.
  38. Carson, Gail
  39. Sigfrid, Louise
  40. Scott, Janet T.
  41. Greenhawt, Matthew
  42. Buonsenso, Danilo
  43. Semple, Malcolm G.
  44. Warner, John O.
  45. Olliaro, Piero
  46. Needham, Dale M.
  47. Glybochko, Petr
  48. Butnaru, Denis
  49. Osmanov, Ismail M.
  50. Munblit, Daniel ORCID logo
  51. Sechenov StopCOVID Research Team

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WeightNameValue
1000 Titel
  • Prevalence and risk factors of post-COVID-19 condition in adults and children at 6 and 12 months after hospital discharge: a prospective, cohort study in Moscow (StopCOVID)
1000 Autor/in
  1. Pazukhina, Ekaterina |
  2. Andreeva, Margarita |
  3. Spiridonova, Ekaterina |
  4. Bobkova, Polina |
  5. Shikhaleva, Anastasia |
  6. El-Taravi, Yasmin |
  7. Rumyantsev, Mikhail |
  8. Gamirova, Aysylu |
  9. Bairashevskaia, Anastasiia |
  10. Petrova, Polina |
  11. Baimukhambetova, Dina |
  12. Pikuza, Maria |
  13. Abdeeva, Elina |
  14. Filippova, Yulia |
  15. Deunezhewa, Salima |
  16. Nekliudov, Nikita |
  17. Bugaeva, Polina |
  18. Bulanov, Nikolay |
  19. Avdeev, Sergey |
  20. Kapustina, Valentina |
  21. Guekht, Alla |
  22. DunnGalvin, Audrey |
  23. Comberiati, Pasquale |
  24. Peroni, Diego G. |
  25. Apfelbacher, Christian |
  26. Genuneit, Jon |
  27. Reyes, Luis Felipe |
  28. Brackel, Caroline L. H. |
  29. Fomin, Victor |
  30. Svistunov, Andrey A. |
  31. Timashev, Peter |
  32. Mazankova, Lyudmila |
  33. Miroshina, Alexandra |
  34. Samitova, Elmira |
  35. Borzakova, Svetlana |
  36. Bondarenko, Elena |
  37. Korsunskiy, Anatoliy A. |
  38. Carson, Gail |
  39. Sigfrid, Louise |
  40. Scott, Janet T. |
  41. Greenhawt, Matthew |
  42. Buonsenso, Danilo |
  43. Semple, Malcolm G. |
  44. Warner, John O. |
  45. Olliaro, Piero |
  46. Needham, Dale M. |
  47. Glybochko, Petr |
  48. Butnaru, Denis |
  49. Osmanov, Ismail M. |
  50. Munblit, Daniel |
  51. Sechenov StopCOVID Research Team |
1000 Erscheinungsjahr 2022
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2022-07-06
1000 Erschienen in
1000 Quellenangabe
  • 20:244
1000 Copyrightjahr
  • 2022
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12916-022-02448-4 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9257572/ |
1000 Ergänzendes Material
  • https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-022-02448-4#Sec10 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • BACKGROUND: Previous studies assessing the prevalence of COVID-19 sequelae in adults and children were performed in the absence of an agreed definition. We investigated prevalence of post-COVID-19 condition (PCC) (WHO definition), at 6- and 12-months follow-up, amongst previously hospitalised adults and children and assessed risk factors. METHODS: Prospective cohort study of children and adults with confirmed COVID-19 in Moscow, hospitalised between April and August, 2020. Two follow-up telephone interviews, using the International Severe Acute Respiratory and Emerging Infection Consortium survey, were performed at 6 and 12 months after discharge. RESULTS: One thousand thirteen of 2509 (40%) of adults and 360 of 849 (42%) of children discharged participated in both the 6- and 12-month follow-ups. PCC prevalence was 50% (95% CI 47–53) in adults and 20% (95% CI 16–24) in children at 6 months, with decline to 34% (95% CI 31–37) and 11% (95% CI 8–14), respectively, at 12 months. In adults, female sex was associated with PCC at 6- and 12-month follow-up (OR 2.04, 95% CI 1.57 to 2.65) and (OR 2.04, 1.54 to 2.69), respectively. Pre-existing hypertension (OR 1.42, 1.04 to 1.94) was associated with post-COVID-19 condition at 12 months. In children, neurological comorbidities were associated with PCC both at 6 months (OR 4.38, 1.36 to 15.67) and 12 months (OR 8.96, 2.55 to 34.82) while allergic respiratory diseases were associated at 12 months (OR 2.66, 1.04 to 6.47). CONCLUSIONS: Although prevalence of PCC declined one year after discharge, one in three adults and one in ten children experienced ongoing sequelae. In adults, females and persons with pre-existing hypertension, and in children, persons with neurological comorbidities or allergic respiratory diseases are at higher risk of PCC.
1000 Sacherschließung
lokal Post-COVID-19 condition
lokal Risk factor
gnd 1206347392 COVID-19
lokal Adults
lokal Prevalence
lokal Post-acute sequelae of SARS-CoV-2 infection
lokal COVID-19 sequelae
lokal Children
lokal Long COVID
lokal PASC
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
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