Checkpoint blocker induced autoimmunity as an indicator for tumour efficacy in melanoma

  1. Hassel, Jessica C.

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1000 Titel
  • Checkpoint blocker induced autoimmunity as an indicator for tumour efficacy in melanoma
1000 Autor/in
  1. Hassel, Jessica C. |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-10-25
1000 Erschienen in
1000 Quellenangabe
  • 126(2):163-164
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1038/s41416-021-01390-1 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770793/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Immune checkpoint inhibitors (ICI) have improved survival of patients with metastatic melanoma but can induce autoimmunologic side effects. Ye et al. report a retrospective analysis that further supports the finding that these are biomarkers for patients' clinical benefit. Thereby, patients with immune-related adverse events show a differential gene expression in chemokine-mediated signalling.
1000 Sacherschließung
lokal Humans [MeSH]
lokal Treatment Outcome [MeSH]
lokal Molecular Medicine
lokal Drug Resistance
lokal Oncology
lokal Editorial
lokal Epidemiology
lokal Survival Rate [MeSH]
lokal Cancer Research
lokal Immune Checkpoint Inhibitors/adverse effects [MeSH]
lokal Melanoma/immunology [MeSH]
lokal Melanoma/pathology [MeSH]
lokal Biomedicine, general
lokal Autoimmunity [MeSH]
lokal Melanoma/drug therapy [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/SGFzc2VsLCBKZXNzaWNhIEMu
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1000 Erstellt am 2023-04-26T16:03:44.111+0200
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1000 Zuletzt bearbeitet 2023-10-19T13:34:04.076+0200
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