EOMES is essential for antitumor activity of CD8+ T cells in chronic lymphocytic leukemia

  1. Llaó-Cid, Laura
  2. Roessner, Philipp M. ORCID logo
  3. Chapaprieta, Vicente ORCID logo
  4. Öztürk, Selcen
  5. Roider, Tobias ORCID logo
  6. Bordas, Marie
  7. Izcue, Ana ORCID logo
  8. COLOMER, DOLORS ORCID logo
  9. Dietrich, Sascha
  10. Stilgenbauer, Stephan
  11. Hanna, Bola
  12. Martin-Subero, Jose Ignacio ORCID logo
  13. Seiffert, Martina ORCID logo

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WeightNameValue
1000 Titel
  • EOMES is essential for antitumor activity of CD8+ T cells in chronic lymphocytic leukemia
1000 Autor/in
  1. Llaó-Cid, Laura |
  2. Roessner, Philipp M. |
  3. Chapaprieta, Vicente |
  4. Öztürk, Selcen |
  5. Roider, Tobias |
  6. Bordas, Marie |
  7. Izcue, Ana |
  8. COLOMER, DOLORS |
  9. Dietrich, Sascha |
  10. Stilgenbauer, Stephan |
  11. Hanna, Bola |
  12. Martin-Subero, Jose Ignacio |
  13. Seiffert, Martina |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-03-17
1000 Erschienen in
1000 Quellenangabe
  • 35(11):3152-3162
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1038/s41375-021-01198-1 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550953/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Genome-wide association studies identified a single-nucleotide polymorphism (SNP) affecting the transcription factor Eomesodermin (EOMES) associated with a significantly increased risk to develop chronic lymphocytic leukemia (CLL). Epigenetic analyses, RNA sequencing, and flow cytometry revealed that EOMES is not expressed in CLL cells, but in CD8
1000 Sacherschließung
lokal Female [MeSH]
lokal Immunosurveillance
lokal T-Box Domain Proteins/genetics [MeSH]
lokal Chronic lymphocytic leukaemia
lokal Mice, Inbred C57BL [MeSH]
lokal Leukemia, Lymphocytic, Chronic, B-Cell/metabolism [MeSH]
lokal Animals [MeSH]
lokal Mice, Knockout [MeSH]
lokal Genome-Wide Association Study [MeSH]
lokal Lymph Nodes/immunology [MeSH]
lokal Mice [MeSH]
lokal Article
lokal Leukemia, Lymphocytic, Chronic, B-Cell/genetics [MeSH]
lokal Leukemia, Lymphocytic, Chronic, B-Cell/immunology [MeSH]
lokal Leukemia, Lymphocytic, Chronic, B-Cell/pathology [MeSH]
lokal Preclinical research
lokal Male [MeSH]
lokal T-Box Domain Proteins/metabolism [MeSH]
lokal T-Box Domain Proteins/physiology [MeSH]
lokal Case-Control Studies [MeSH]
lokal CD8-Positive T-Lymphocytes/immunology [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/TGxhw7MtQ2lkLCBMYXVyYQ==|https://orcid.org/0000-0001-7061-5690|https://orcid.org/0000-0002-4910-5394|https://frl.publisso.de/adhoc/uri/w5Z6dMO8cmssIFNlbGNlbg==|https://orcid.org/0000-0002-6973-3531|https://frl.publisso.de/adhoc/uri/Qm9yZGFzLCBNYXJpZQ==|https://orcid.org/0000-0002-7974-7451|https://orcid.org/0000-0001-7486-8484|https://frl.publisso.de/adhoc/uri/RGlldHJpY2gsIFNhc2NoYQ==|https://frl.publisso.de/adhoc/uri/U3RpbGdlbmJhdWVyLCBTdGVwaGFu|https://frl.publisso.de/adhoc/uri/SGFubmEsIEJvbGE=|https://orcid.org/0000-0001-8809-5195|https://orcid.org/0000-0001-5155-663X
1000 Hinweis
  • DeepGreen-ID: 92819ebf758941e9a6a073db3a0f4bf1 ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
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1000 @id frl:6443846.rdf
1000 Erstellt am 2023-04-27T11:03:12.457+0200
1000 Erstellt von 322
1000 beschreibt frl:6443846
1000 Zuletzt bearbeitet Fri Oct 20 11:34:31 CEST 2023
1000 Objekt bearb. Fri Oct 20 11:34:31 CEST 2023
1000 Vgl. frl:6443846
1000 Oai Id
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