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1000 Titel
  • Safety, Mortality, and Hemodynamic Impact of Patients with MitraClip Undergoing Left Ventricular Assist Device Implantation
1000 Autor/in
  1. Fox, Henrik |
  2. Gyoten, Takayuki |
  3. Rojas, Sebastian V. |
  4. Deutsch, Marcus-André |
  5. Schramm, René |
  6. Rudolph, Volker |
  7. Gummert, Jan F. |
  8. Morshuis, Michiel |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-10-28
1000 Erschienen in
1000 Quellenangabe
  • 15(3):676-686
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s12265-021-10178-w |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213377/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • The interactions and hemodynamic impact of transcatheter percutaneous mitral valve repair (TMR) have not yet been investigated in patients undergoing left ventricular assist device (LVAD) implantation, but hemodynamic adverse effects are feared in the combination of TMR and LVAD for altered mitral valve flow. This study investigated the hemodynamic interplay in combination of TMR and LVAD in 119 patients, and propensity score match analysis revealed no difference in both perioperative mortality and 2-year follow-up survival (p = 0.84). Nonetheless, postoperatively mean pulmonary arterial pressure, pulmonary capillary wedge pressure, and cardiac index improved, and multivariable cox regression analysis at 2 years identified preoperative total bilirubin and temporary right ventricular mechanical circulatory support as independent risk factors for all-cause mortality but not TMR. Prior TMR has no impact on mortality or cardiovascular complications in patients with LVAD.
1000 Sacherschließung
lokal Cardiac Surgical Procedures/adverse effects [MeSH]
lokal Heart failure
lokal Transpulmonary gradient
lokal Humans [MeSH]
lokal Treatment Outcome [MeSH]
lokal Retrospective Studies [MeSH]
lokal Left ventricular dysfunction
lokal Heart-Assist Devices/adverse effects [MeSH]
lokal MitraClip
lokal Heart Failure/surgery [MeSH]
lokal Ventricular Dysfunction, Right [MeSH]
lokal Original Article
lokal Pulmonary Wedge Pressure [MeSH]
lokal Pulmonary vascular resistance
lokal Heart transplantation
lokal HeartMate 3
lokal Mortality
lokal CentriMag system
lokal Pulmonary artery pressure
lokal Heart Failure/diagnosis [MeSH]
lokal Left ventricular assist device
lokal Mechanical circulatory support
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-2187-8715|https://frl.publisso.de/adhoc/uri/R3lvdGVuLCBUYWtheXVraQ==|https://frl.publisso.de/adhoc/uri/Um9qYXMsIFNlYmFzdGlhbiBWLg==|https://frl.publisso.de/adhoc/uri/RGV1dHNjaCwgTWFyY3VzLUFuZHLDqQ==|https://frl.publisso.de/adhoc/uri/U2NocmFtbSwgUmVuw6k=|https://frl.publisso.de/adhoc/uri/UnVkb2xwaCwgVm9sa2Vy|https://frl.publisso.de/adhoc/uri/R3VtbWVydCwgSmFuIEYu|https://frl.publisso.de/adhoc/uri/TW9yc2h1aXMsIE1pY2hpZWw=
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1000 Erstellt am 2023-04-27T12:32:07.035+0200
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1000 Zuletzt bearbeitet Fri Oct 20 12:16:30 CEST 2023
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