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1000 Titel
  • Herausforderungen der Therapie thorakaler Schmerzen bei zystischer Fibrose (CF)
1000 Titelzusatz
  • The challenges of managing thoracic pain in cystic fibrosis (CF)
1000 Autor/in
  1. Hoffmann, A. T. |
  2. Dillenhöfer, S. |
  3. Lücke, T. |
  4. Maier, C. |
  5. Brinkmann, F. |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-11-11
1000 Erschienen in
1000 Quellenangabe
  • 36(6):422-428
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00482-021-00603-z |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674729/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!Cystic fibrosis (CF) is a rare genetic multisystemic disorder with progressive abdominal and pulmonary involvement. Pain is still an underestimated symptom in CF patients.!##!Methods!#!A comprehensive review of guidelines and scientific literature on the topic was performed and combined with findings from pain management in a young CF patient with progressive thoracic pain.!##!Results!#!German CF guidelines do not cover diagnosis and management of pain in these patients. Studies from Europe and the United States report interactions between intensity of pain and mortality in CF, but do not include data on the efficacy of pain management. These data and clinical observations of a CF patient with episodes of intense thoracic pain are used to illustrate the specific challenges in pain relief.!##!Conclusion!#!Pain management in CF requires meticulous monitoring as well as an interdisciplinary approach and should be implemented in the German CF guidelines. The authors also want to suggest recommendations for the treatment of thoracic pain in CF. The range and severity of organ involvement complicates the use both of opioids and non-opioids. Especially opioid treatment carries the risk of hypoxia and opioid-induced constipation (OIC) and needs close medical supervision.
1000 Sacherschließung
lokal Analgesics, Opioid/adverse effects [MeSH]
lokal Kinder
lokal Hypoxia
lokal United States [MeSH]
lokal Cystic Fibrosis/complications [MeSH]
lokal Humans [MeSH]
lokal Hypoxie
lokal Opioids
lokal Adverse event
lokal Pain Management [MeSH]
lokal Opioide
lokal Pain/drug therapy [MeSH]
lokal Originalien
lokal Children
lokal Epiduralkatheter
lokal Constipation [MeSH]
lokal Cystic Fibrosis/diagnosis [MeSH]
lokal Nebenwirkung
lokal Cystic Fibrosis/therapy [MeSH]
lokal Epidural catether
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/SG9mZm1hbm4sIEEuIFQu|https://frl.publisso.de/adhoc/uri/RGlsbGVuaMO2ZmVyLCBTLg==|https://frl.publisso.de/adhoc/uri/TMO8Y2tlLCBULg==|https://frl.publisso.de/adhoc/uri/TWFpZXIsIEMu|https://frl.publisso.de/adhoc/uri/QnJpbmttYW5uLCBGLg==
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1000 Erstellt am 2023-04-28T13:56:26.110+0200
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1000 Zuletzt bearbeitet Fri Oct 20 18:50:10 CEST 2023
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