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1000 Titel
  • Progress in the implementation of massively parallel sequencing for forensic genetics: results of a European-wide survey among professional users
1000 Autor/in
  1. Gross, Theresa E. |
  2. Fleckhaus, Jan |
  3. Schneider, Peter M. |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-04-13
1000 Erschienen in
1000 Quellenangabe
  • 135(4):1425-1432
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00414-021-02569-0 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205868/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • A European-wide online survey was conducted to generate an overview on the state-of-the-art using massively parallel sequencing (MPS) platforms for forensic DNA analysis and DNA phenotyping among forensic practitioners in Europe. The survey was part of the dissemination activities of the 'VISible Attributes through GEnomics - VISAGE' Horizon 2020 funded European research project [30], in preparation of a series of educational training activities. A total of 105 replies from 32 European countries representing participants from police, governmental, academic, and private laboratories providing professional services in the field of forensic genetics were included in the final analysis. Of these, 73% already own an MPS platform or are planning to acquire one within the next 1-2 years. One-third of the participants have already carried out MPS-based STR sequencing, identity, or ancestry SNP typing. A total of 23-40% of participants are planning to explore all FDP applications showing the overall very high interest in using MPS for the whole range of forensic MPS markers and applications. About 50% of the participants have previously gathered experience using forensic DNA phenotyping (FDP) markers based on conventional (i.e., not MPS-based) DNA typing methods. A total of 55% of the participants have attended training on the general use of MPS technology, but 36% have received no training whatsoever. Accordingly, 90% have expressed high or medium interest to attend training on the analysis and interpretation of DNA phenotyping data for predicting appearance, ancestry, and age. The results of our survey will provide valuable information for organizing relevant training workshops on all aspects of MPS-based DNA phenotyping for the forensic genetics scientific community.
1000 Sacherschließung
lokal Surveys and Questionnaires [MeSH]
lokal Europe [MeSH]
lokal Forensic DNA casework
lokal Laboratories/organization
lokal Humans [MeSH]
lokal DNA phenotyping
lokal Forensic Genetics/education [MeSH]
lokal Online survey
lokal Forensic Genetics/methods [MeSH]
lokal Next-generation sequencing
lokal Sequence Analysis, DNA [MeSH]
lokal DNA Fingerprinting/methods [MeSH]
lokal Short Communication
lokal High-Throughput Nucleotide Sequencing [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/R3Jvc3MsIFRoZXJlc2EgRS4=|https://frl.publisso.de/adhoc/uri/RmxlY2toYXVzLCBKYW4=|https://orcid.org/0000-0003-0744-2349
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1000 Erstellt am 2023-04-28T15:15:14.875+0200
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1000 Zuletzt bearbeitet Fri Oct 20 19:57:19 CEST 2023
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