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1000 Titel
  • Single-stage total hip arthroplasty after failed fixation of proximal femoral fractures: an increased risk for periprosthetic joint infections?
1000 Autor/in
  1. Hemmann, P. |
  2. Schmidutz, F. |
  3. Ahrend, M. D. |
  4. Yan, S. G. |
  5. Stöckle, U. |
  6. Schreiner, A. J. |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-08-28
1000 Erschienen in
1000 Quellenangabe
  • 142(10):2911-2917
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00402-021-04119-0 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474588/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!Higher complication rates have been reported for total hip arthroplasty (THA) after osteosynthesis of proximal femur fractures (PFF). This study evaluated the infection risk for conversion of internal fixation of PFF to THA by a single-staged procedure in the absence of clear infection signs.!##!Methods!#!Patients undergoing a one-staged conversion to THA (2013-2018) after prior internal fixation of the proximal femur were included. Preoperative diagnostics with laboratory results, hip aspirations as well as intraoperative microbiology and sonication were assessed. Postoperative complications were recorded as well as patient demographics, duration between initial and conversion to THA, explanted osteosynthesis and implanted THA.!##!Results!#!Fifty-eight patients (24 male/34 female, 62.8 ± 14.5 years) were included with a mean time of 3.8 ± 7.5 years between internal fixation and conversion to THA (45 cementless, 3 cemented, 3 hybrid and 7 hybrid inverse THAs). Preoperative mean blood level CRP was 8.36 ± 14 mg/l (reference value < 5 mg/l) and leukocyte count was 7.11 ± 1.84^3/µl (4.5-10.000^3/µl). Fifty patients had intraoperative microbiological diagnostics, with either swabs in 86.2% and/or sonication in 29.3%. Positive microbiological results were recorded in 10% (5 of 50 patients), with pathogens identified being mainly Staphylococcus. Complications after conversion occurred in 9.6% including a postoperative low-grade infection rate of 5.8% after a mean of 2.5 years.!##!Conclusion!#!This study found a positive microbiological test result in 10% of a one-stage conversion of PFF fixation to THA. Moreover, we found a high infection rate (5.8%) for early postoperative periprosthetic joint infection. Interestingly, CRP has not been proven to be an adequate parameter for low-grade infections or occult colonized implants. Therefore, we recommend a comprehensive pre- and intraoperative diagnostic including hip aspiration, swabs and sonication when considering one-staged revision.
1000 Sacherschließung
lokal Female [MeSH]
lokal Hip Prosthesis/adverse effects [MeSH]
lokal Humans [MeSH]
lokal Retrospective Studies [MeSH]
lokal Risk Factors [MeSH]
lokal Diagnostics
lokal Periprosthetic Fractures/surgery [MeSH]
lokal Reoperation/adverse effects [MeSH]
lokal PJI
lokal Infection
lokal Femoral Fractures/surgery [MeSH]
lokal Male [MeSH]
lokal Hip Arthroplasty
lokal Arthroplasty, Replacement, Hip/methods [MeSH]
lokal Arthroplasty, Replacement, Hip/adverse effects [MeSH]
lokal Arthritis, Infectious/surgery [MeSH]
lokal Postoperative Complications/etiology [MeSH]
lokal Femoral fracture
lokal Periprosthetic Fractures/etiology [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/SGVtbWFubiwgUC4=|https://frl.publisso.de/adhoc/uri/U2NobWlkdXR6LCBGLg==|https://frl.publisso.de/adhoc/uri/QWhyZW5kLCBNLiBELg==|https://frl.publisso.de/adhoc/uri/WWFuLCBTLiBHLg==|https://frl.publisso.de/adhoc/uri/U3TDtmNrbGUsIFUu|https://frl.publisso.de/adhoc/uri/U2NocmVpbmVyLCBBLiBKLg==
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1000 Erstellt am 2023-04-28T15:43:23.949+0200
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1000 Zuletzt bearbeitet 2023-10-20T20:26:55.827+0200
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