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1000 Titel
  • What is known about palliative care in adult patients with allogeneic stem cell transplantation (allo-SCT)?
1000 Autor/in
  1. Simon, Steffen T. |
  2. Pralong, Anne |
  3. Hallek, Michael |
  4. Scheid, Christoph |
  5. Holtick, Udo |
  6. Herling, Marco |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-05-06
1000 Erschienen in
1000 Quellenangabe
  • 100(6):1377-1389
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00277-021-04538-4 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116288/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Patients undergoing allogeneic stem cell transplantation (allo-SCT) are given a real chance of cure, but at the same time are confronted with a considerable risk of mortality and of severe long-term impediments. This narrative, non-systematic literature review aims to describe the supportive and palliative care needs of allo-SCT recipients, including long-term survivors or those relapsing or dying after transplantation. It also evaluates the feasibility and effectivity of integrating palliative care early in transplant procedures. In this appraisal of available literature, the main findings relate to symptoms like fatigue and psychological distress, which appear to be very common in the whole allo-SCT trajectory and might even persist many years post-transplantation. Chronic GvHD has a major negative impact on quality of life. Overall, there is a paucity of research on further issues in the context of allo-SCT, like the distress related to the frequently unpredictable post-transplant trajectory and prognosis, as well as the end-of-life phase. First randomized controlled results support the effectiveness of early integration of specialized palliative care expertise into transplant algorithms. Barriers to this implementation are discussed.
1000 Sacherschließung
lokal Fatigue/epidemiology [MeSH]
lokal Transplantation, Homologous/methods [MeSH]
lokal Psychological Distress [MeSH]
lokal Humans [MeSH]
lokal Review Article
lokal Hematopoietic Stem Cell Transplantation/adverse effects [MeSH]
lokal Supportive care
lokal Transplantation, Homologous/adverse effects [MeSH]
lokal Palliative Care/methods [MeSH]
lokal Quality of life
lokal Graft vs Host Disease/epidemiology [MeSH]
lokal Palliative medicine
lokal Quality of Life [MeSH]
lokal Chronic Disease [MeSH]
lokal Hematopoietic Stem Cell Transplantation/methods [MeSH]
lokal Allogeneic transplantation
lokal Stem cell transplantation
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/U2ltb24sIFN0ZWZmZW4gVC4=|https://orcid.org/0000-0001-8201-2344|https://frl.publisso.de/adhoc/uri/SGFsbGVrLCBNaWNoYWVs|https://frl.publisso.de/adhoc/uri/U2NoZWlkLCBDaHJpc3RvcGg=|https://frl.publisso.de/adhoc/uri/SG9sdGljaywgVWRv|https://frl.publisso.de/adhoc/uri/SGVybGluZywgTWFyY28=
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1000 Erstellt am 2023-05-03T16:31:23.196+0200
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