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1000 Titel
  • Impact of DMEK on visual quality in patients with Fuchs’ endothelial dystrophy
1000 Autor/in
  1. Ademmer, Vanessa |
  2. Agha, Bishr |
  3. Shajari, Mehdi |
  4. Kohnen, Thomas |
  5. Schmack, Ingo |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-09-16
1000 Erschienen in
1000 Quellenangabe
  • 260(2):521-528
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00417-021-05334-6 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786756/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!To investigate short-term (3 months follow-up) changes in visual quality following Descemet membrane endothelial keratoplasty (DMEK) for Fuchs endothelial dystrophy (FED).!##!Methods!#!In this prospective institutional case series, 51 patients that underwent DMEK for FED were included. Assessment included the Quality of Vision (QoV) questionnaire preoperatively, at 1 month, and 3 months after surgery. Secondary outcome measures were anterior segment parameters acquired by Scheimpflug imaging, corrected distance visual acuity (CDVA), and endothelial cell density (ECD).!##!Results!#!Glare, hazy vision, blurred vision, and daily fluctuation in vision were the symptoms mostly reported preoperatively. All symptoms demonstrated a significant reduction of item scores for severity, frequency, and bothersome in the course after DMEK (P < 0.01). Glare and fluctuation in vision remained to some extent during the follow-up period (median score = 1). Preoperatively, corneal densitometry correlated moderately to weakly with severity of hazy vision (r!##!Conclusions!#!Following DMEK for FED, patient-reported visual symptoms assessed by the QoV questionnaire represent a useful tool providing valuable information on the impact of DMEK on visual quality that cannot be directly estimated by morphological parameters and visual acuity only.
1000 Sacherschließung
lokal Cornea [MeSH]
lokal Endothelium, Corneal [MeSH]
lokal Humans [MeSH]
lokal Prospective Studies [MeSH]
lokal Visual quality
lokal Retrospective Studies [MeSH]
lokal Cornea
lokal Visual Acuity [MeSH]
lokal Fuchs' Endothelial Dystrophy/surgery [MeSH]
lokal Scheimpflug imaging
lokal DMEK
lokal Descemet Stripping Endothelial Keratoplasty [MeSH]
lokal Fuchs endothelial dystrophy
lokal Cell Count [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/QWRlbW1lciwgVmFuZXNzYQ==|https://frl.publisso.de/adhoc/uri/QWdoYSwgQmlzaHI=|https://frl.publisso.de/adhoc/uri/U2hhamFyaSwgTWVoZGk=|https://orcid.org/0000-0002-6933-9585|https://frl.publisso.de/adhoc/uri/U2NobWFjaywgSW5nbw==
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1000 Erstellt am 2023-05-09T11:19:55.839+0200
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1000 Zuletzt bearbeitet Sat Oct 21 02:50:03 CEST 2023
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