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1000 Titel
  • The Role of Visceral Obesity, Sarcopenia and Sarcopenic Obesity on Surgical Outcomes After Liver Resections for Colorectal Metastases
1000 Autor/in
  1. Runkel, M. |
  2. Diallo, T. D. |
  3. Lang, S. A. |
  4. Bamberg, F. |
  5. Benndorf, M. |
  6. Fichtner-Feigl, S. |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-04-11
1000 Erschienen in
1000 Quellenangabe
  • 45(7):2218-2226
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00268-021-06073-9 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154807/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!The impact of body compositions on surgical results is controversially discussed. This study examined whether visceral obesity, sarcopenia or sarcopenic obesity influence the outcome after hepatic resections of synchronous colorectal liver metastases.!##!Methods!#!Ninety-four consecutive patients with primary hepatic resections of synchronous colorectal metastases were identified from a single center database between January 2013 and August 2018. Patient characteristics and 30-day morbidity were retrospectively analyzed. Body fat and skeletal muscle were calculated by planimetry from single-slice CT images at the level of L3.!##!Results!#!Fifty-nine patients (62.8%) underwent minor hepatectomies, and 35 patients underwent major resections (37.2%). Postoperative complications occurred in 60 patients (62.8%) including 35 patients with major complications (Clavien-Dindo grade III-V). The mortality was nil at 30 days and 2.1% at 90 days. The body mass index showed no influence on postoperative outcomes (p = 1.0). Visceral obesity was found in 66 patients (70.2%) and was significantly associated with overall and major complication rates (p = .002, p = .012, respectively). Sarcopenia was observed in 34 patients (36.2%) without a significant impact on morbidity (p = .461), however, with longer hospital stay. Sarcopenic obesity was found in 18 patients (19.1%) and was significantly associated with postoperative complications (p = .014). Visceral obesity, sarcopenia and sarcopenic obesity were all identified as significant risk factors for overall postoperative complications.!##!Conclusion!#!Visceral obesity, sarcopenic obesity and sarcopenia are independent risk factors for overall complications after resections of CRLM. Early recognition of extremes in body compositions could prompt to perioperative interventions and thus improve postoperative outcomes.
1000 Sacherschließung
lokal Obesity, Abdominal [MeSH]
lokal Liver [MeSH]
lokal Vascular Surgery
lokal Humans [MeSH]
lokal Treatment Outcome [MeSH]
lokal Thoracic Surgery
lokal Colorectal Neoplasms/surgery [MeSH]
lokal Postoperative Complications/epidemiology [MeSH]
lokal Retrospective Studies [MeSH]
lokal General Surgery
lokal Risk Factors [MeSH]
lokal Cardiac Surgery
lokal Original Scientific Report
lokal Obesity/complications [MeSH]
lokal Hepatectomy/adverse effects [MeSH]
lokal Colorectal Neoplasms/complications [MeSH]
lokal Sarcopenia/complications [MeSH]
lokal Abdominal Surgery
lokal Sarcopenia/epidemiology [MeSH]
lokal Surgery
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  1. https://frl.publisso.de/adhoc/uri/UnVua2VsLCBNLg==|https://frl.publisso.de/adhoc/uri/RGlhbGxvLCBULiBELg==|https://frl.publisso.de/adhoc/uri/TGFuZywgUy4gQS4=|https://frl.publisso.de/adhoc/uri/QmFtYmVyZywgRi4=|https://frl.publisso.de/adhoc/uri/QmVubmRvcmYsIE0u|https://frl.publisso.de/adhoc/uri/RmljaHRuZXItRmVpZ2wsIFMu
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1000 Erstellt am 2023-05-11T13:05:19.582+0200
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1000 Zuletzt bearbeitet Sat Oct 21 04:42:01 CEST 2023
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