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1000 Titel
  • Rhinovirus prevalence as indicator for efficacy of measures against SARS-CoV-2
1000 Autor/in
  1. Kitanovski, Simo |
  2. Horemheb-Rubio, Gibran |
  3. Adams, Ortwin |
  4. Gärtner, Barbara |
  5. Lengauer, Thomas |
  6. Hoffmann, Daniel |
  7. Kaiser, Rolf |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-06-21
1000 Erschienen in
1000 Quellenangabe
  • 21(1):1178
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12889-021-11178-w |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215636/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!Non-pharmaceutical measures to control the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) should be carefully tuned as they can impose a heavy social and economic burden. To quantify and possibly tune the efficacy of these anti-SARS-CoV-2 measures, we have devised indicators based on the abundant historic and current prevalence data from other respiratory viruses.!##!Methods!#!We obtained incidence data of 17 respiratory viruses from hospitalized patients and outpatients collected by 37 clinics and laboratories between 2010-2020 in Germany. With a probabilistic model for Bayes inference we quantified prevalence changes of the different viruses between months in the pre-pandemic period 2010-2019 and the corresponding months in 2020, the year of the pandemic with noninvasive measures of various degrees of stringency.!##!Results!#!We discovered remarkable reductions δ in rhinovirus (RV) prevalence by about 25% (95% highest density interval (HDI) [-0.35,-0.15]) in the months after the measures against SARS-CoV-2 were introduced in Germany. In the months after the measures began to ease, RV prevalence increased to low pre-pandemic levels, e.g. in August 2020 δ=-0.14 (95% HDI [-0.28,0.12]).!##!Conclusions!#!RV prevalence is negatively correlated with the stringency of anti-SARS-CoV-2 measures with only a short time delay. This result suggests that RV prevalence could possibly be an indicator for the efficiency for these measures. As RV is ubiquitous at higher prevalence than SARS-CoV-2 or other emerging respiratory viruses, it could reflect the efficacy of noninvasive measures better than such emerging viruses themselves with their unevenly spreading clusters.
1000 Sacherschließung
gnd 1206347392 COVID-19
lokal Humans [MeSH]
lokal Germany
lokal Rhinovirus [MeSH]
lokal COVID-19
lokal Bayes Theorem [MeSH]
lokal Bayesian
lokal Modeling
lokal Research
lokal Rhinovirus
lokal COVID-19 [MeSH]
lokal Germany [MeSH]
lokal Prevalence [MeSH]
lokal SARS-CoV-2 [MeSH]
lokal SARS-CoV-2
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/S2l0YW5vdnNraSwgU2ltbw==|https://frl.publisso.de/adhoc/uri/SG9yZW1oZWItUnViaW8sIEdpYnJhbg==|https://frl.publisso.de/adhoc/uri/QWRhbXMsIE9ydHdpbg==|https://frl.publisso.de/adhoc/uri/R8OkcnRuZXIsIEJhcmJhcmE=|https://frl.publisso.de/adhoc/uri/TGVuZ2F1ZXIsIFRob21hcw==|https://frl.publisso.de/adhoc/uri/SG9mZm1hbm4sIERhbmllbA==|https://frl.publisso.de/adhoc/uri/S2Fpc2VyLCBSb2xm
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1000 Erstellt am 2023-11-15T13:17:18.098+0100
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