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1000 Titel
  • Intraoperative blood loss as indicated by haemoglobin trend is a predictor for the development of postoperative spinal implant infection—a matched-pair analysis
1000 Autor/in
  1. Schömig, Friederike |
  2. Bürger, Justus |
  3. Hu, Zhouyang |
  4. Pruß, Axel |
  5. Klotz, Edda |
  6. Pumberger, Matthias |
  7. Hipfl, Christian |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-06-18
1000 Erschienen in
1000 Quellenangabe
  • 16(1):393
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s13018-021-02537-9 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212517/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!With a reported rate of 0.7-20%, postoperative spinal implant infection (PSII) is one of the most common complications after spine surgery. While in arthroplasty both haematoma formation and perioperative blood loss have been identified as risk factors for developing periprosthetic joint infections and preoperative anaemia has been associated with increased complication rates, literature on the aetiology of PSII remains limited.!##!Methods!#!We performed a matched-pair analysis of perioperative haemoglobin (Hb) and haematocrit (Hct) levels in aseptic and septic spine revision surgeries. 317 patients were included, 94 of which were classified as septic according to previously defined criteria. Patients were matched according to age, body mass index, diabetes, American Society of Anesthesiologists score and smoking habits. Descriptive summaries for septic and aseptic groups were analysed using Pearson chi-squared for categorical or Student t test for continuous variables.!##!Results!#!Fifty patients were matched and did not differ significantly in their reason for revision, mean length of hospital stay, blood transfusion, operating time, or number of levels operated on. While there was no significant difference in preoperative Hb or Hct levels, the mean difference between pre- and postoperative Hb was higher in the septic group (3.45 ± 1.25 vs. 2.82 ± 1.48 g/dL, p = 0.034).!##!Conclusions!#!We therefore show that the intraoperative Hb-trend is a predictor for the development of PSII independent of the amount of blood transfusions, operation time, number of spinal levels operated on and hospital length of stay, which is why strategies to reduce intraoperative blood loss in spine surgery need to be further studied.
1000 Sacherschließung
lokal Prosthesis-Related Infections/etiology [MeSH]
lokal Length of Stay/statistics
lokal Aged [MeSH]
lokal Anemia
lokal Risk Factors [MeSH]
lokal Male [MeSH]
lokal Diagnosis
lokal Blood Transfusion/statistics
lokal Spine/surgery [MeSH]
lokal Research Article
lokal Intraoperative Period [MeSH]
lokal Orthopaedic surgery
lokal Reoperation/statistics
lokal Female [MeSH]
lokal Humans [MeSH]
lokal Hemoglobins/analysis [MeSH]
lokal Predictive Value of Tests [MeSH]
lokal Retrospective Studies [MeSH]
lokal Middle Aged [MeSH]
lokal Infection
lokal Sepsis/etiology [MeSH]
lokal Matched-Pair Analysis [MeSH]
lokal Spine
lokal Hematocrit/statistics
lokal Blood Loss, Surgical/statistics
lokal Operative Time [MeSH]
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-9224-7363|https://frl.publisso.de/adhoc/uri/QsO8cmdlciwgSnVzdHVz|https://frl.publisso.de/adhoc/uri/SHUsIFpob3V5YW5n|https://frl.publisso.de/adhoc/uri/UHJ1w58sIEF4ZWw=|https://frl.publisso.de/adhoc/uri/S2xvdHosIEVkZGE=|https://frl.publisso.de/adhoc/uri/UHVtYmVyZ2VyLCBNYXR0aGlhcw==|https://frl.publisso.de/adhoc/uri/SGlwZmwsIENocmlzdGlhbg==
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1000 Erstellt am 2023-11-15T18:57:11.744+0100
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