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1000 Titel
  • Alemtuzumab-associated diffuse alveolar damage – a case report
1000 Autor/in
  1. Bayas, Antonios |
  2. Menacher, Martina |
  3. Schwaiblmair, Martin |
  4. Märkl, Bruno |
  5. Naumann, Markus |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-09-23
1000 Erschienen in
1000 Quellenangabe
  • 20(1):357
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12883-020-01934-7 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510011/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!Identifying causes of alemtuzumab induced respiratory symptoms in Multiple Sclerosis (MS) patients is crucial.!##!Case presentation!#!We report a case of diffuse alveolar damage (DAD) in a patient with MS after the first course of alemtuzumab treatment. A 42-year-old female developed progressive non-productive cough and exertional dyspnea 2 months after alemtuzumab treatment. DAD was diagnosed histopathologically by lung biopsy. The patient recovered completely, alemtuzumab was not continued.!##!Conclusions!#!Our case highlights another pathomechanism for non-infective lung-disorders in alemtuzumab treated MS patients. DAD is a potential, albeit rare side effect of alemtuzumab, broadening the spectrum of non-infective lung disorders that should be considered in the diagnostic work-up.
1000 Sacherschließung
lokal Antineoplastic Agents, Immunological/adverse effects [MeSH]
lokal Female [MeSH]
lokal Demyelinating diseases
lokal Adult [MeSH]
lokal Humans [MeSH]
lokal Case report
lokal Lung Diseases, Interstitial/chemically induced [MeSH]
lokal Alemtuzumab/adverse effects [MeSH]
lokal Multiple sclerosis
lokal Multiple Sclerosis, Relapsing-Remitting/drug therapy [MeSH]
lokal Diffuse alveolar damage
lokal Alemtuzumab
lokal Pulmonary Alveoli/pathology [MeSH]
lokal Case Report
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-7418-9040|https://frl.publisso.de/adhoc/uri/TWVuYWNoZXIsIE1hcnRpbmE=|https://frl.publisso.de/adhoc/uri/U2Nod2FpYmxtYWlyLCBNYXJ0aW4=|https://frl.publisso.de/adhoc/uri/TcOkcmtsLCBCcnVubw==|https://frl.publisso.de/adhoc/uri/TmF1bWFubiwgTWFya3Vz
1000 Hinweis
  • DeepGreen-ID: d3490177d3704865b1e77670a7b2c22b ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
1000 Label
1000 Dateien
  1. Alemtuzumab-associated diffuse alveolar damage – a case report
1000 Objektart article
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1000 @id frl:6464581.rdf
1000 Erstellt am 2023-11-16T05:20:33.311+0100
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1000 Zuletzt bearbeitet Fri Dec 01 00:18:34 CET 2023
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