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1000 Titel
  • Radiological and mid- to long-term patient-reported outcome after stabilization of traumatic thoraco-lumbar spinal fractures using an expandable vertebral body replacement implant
1000 Autor/in
  1. Lang, Siegmund |
  2. Neumann, Carsten |
  3. Schwaiger, Christina |
  4. Voss, Andreas |
  5. Alt, Volker |
  6. Loibl, Markus |
  7. Lang, Siegmund |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-08-30
1000 Erschienen in
1000 Quellenangabe
  • 22(1):744
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12891-021-04585-y |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407019/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!For the treatment of unstable thoraco-lumbar burst fractures, a combined posterior and anterior stabilization instead of a posterior-only instrumentation is recommend in the current literature due to the instability of the anterior column. Data on restoring the bi-segmental kyphotic endplate angle (BKA) with expandable vertebral body replacements (VBR) and on the mid- to long-term patient-reported outcome measures (PROM) is sparse.!##!Methods!#!A retrospective cohort study of patients with traumatic thoraco-lumbar spinal fractures treated with an expandable VBR implant (Obelisc™, Ulrich Medical, Germany) between 2001 and 2015 was conducted. Patient and treatment characteristics were evaluated retrospectively. Radiological data acquisition was completed pre- and postoperatively, 6 months and at least 2 years after the VBR surgery. The BKA was measured and fusion-rates were assessed. The SF-36, EQ-5D and ODI questionnaires were evaluated prospectively.!##!Results!#!Ninety-six patients (25 female, 71 male; age: 46.1 ± 12.8 years) were included in the study. An AO Type A4 fracture was seen in 80/96 cases (83.3%). Seventy-three fractures (76.0%) were located at the lumbar spine. Intraoperative reduction of the BKA in n = 96 patients was 10.5 ± 9.4° (p < 0.01). A loss of correction of 1.0 ± 2.8° at the first follow-up (t1) and of 2.4 ± 4.0° at the second follow-up (t2) was measured (each p < 0.05). The bony fusion rate was 97.9%. The total revision rate was 4.2%. Fifty-one patients (53.1% of included patients; age: 48.9 ± 12.4 years) completed the PROM questionnaires after 106.4 ± 44.3 months and therefore were assigned to the respondent group. The mean ODI score was 28.2 ± 18.3%, the mean EQ-5D VAS reached 60.7 ± 4.1 points. Stratified SF-36 results (ISS < and ≥ 16) were lower compared to a reference population.!##!Conclusion!#!The treatment of traumatic thoraco-lumbar fractures with an expandable VBR implant lead to a high rate of bony fusion. A significant correction of the BKA could be achieved and no clinically relevant loss of reduction occurred during the follow-up. Even though health related quality of life did not reach the normative population values, overall satisfactory results were reported.
1000 Sacherschließung
lokal Spinal Fusion/adverse effects [MeSH]
lokal Thoracic Vertebrae/surgery [MeSH]
lokal Posterior-anterior stabilization
lokal Male [MeSH]
lokal Vertebral Body [MeSH]
lokal Quality of Life [MeSH]
lokal Lumbar Vertebrae/diagnostic imaging [MeSH]
lokal Thoraco-lumbar spinal fractures
lokal Spinal Fractures/surgery [MeSH]
lokal Research Article
lokal Expandable vertebral body replacement
lokal Female [MeSH]
lokal Thoracic Vertebrae/injuries [MeSH]
lokal Adult [MeSH]
lokal Humans [MeSH]
lokal Lumbar Vertebrae/injuries [MeSH]
lokal Treatment Outcome [MeSH]
lokal Retrospective Studies [MeSH]
lokal Middle Aged [MeSH]
lokal Patient-reported outcome measures
lokal Health related quality of life
lokal Bony fusion rate
lokal Patient Reported Outcome Measures [MeSH]
lokal Thoracic Vertebrae/diagnostic imaging [MeSH]
lokal Lumbar Vertebrae/surgery [MeSH]
lokal Orthopedics and biomechanics
lokal Spinal Fractures/diagnostic imaging [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/TGFuZywgU2llZ211bmQ=|https://frl.publisso.de/adhoc/uri/TmV1bWFubiwgQ2Fyc3Rlbg==|https://frl.publisso.de/adhoc/uri/U2Nod2FpZ2VyLCBDaHJpc3RpbmE=|https://frl.publisso.de/adhoc/uri/Vm9zcywgQW5kcmVhcw==|https://frl.publisso.de/adhoc/uri/QWx0LCBWb2xrZXI=|https://frl.publisso.de/adhoc/uri/TG9pYmwsIE1hcmt1cw==|https://orcid.org/0000-0003-0459-9092
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