Impact of the COVID-19 pandemic on cardiovascular mortality and catherization activity during the lockdown in central Germany: an observational study

  1. Nef, Holger M.
  2. Elsässer, Albrecht
  3. Möllmann, Helge
  4. Abdel-Hadi, Mohammed
  5. Bauer, Timm
  6. Brück, Martin
  7. Eggebrecht, Holger
  8. Ehrlich, Joachim R.
  9. Ferrari, Markus W.
  10. Fichtlscherer, Stephan
  11. Hink, Ulrich
  12. Hölschermann, Hans
  13. Kacapor, Rifat
  14. Koeth, Oliver
  15. Korboukov, Serguei
  16. Lamparter, Steffen
  17. Laspoulas, Alexander J.
  18. Lehmann, Ralf
  19. Liebetrau, Christoph
  20. Plücker, Tobias
  21. Pons-Kühnemann, Jörn
  22. Schächinger, Volker
  23. Schieffer, Bernhard
  24. Schott, Peter
  25. Schulze, Matthias
  26. Teupe, Claudius
  27. Vasa-Nicotera, Mariuca
  28. Weber, Michael
  29. Weinbrenner, Christoph
  30. Werner, Gerald
  31. Hamm, Christian W.
  32. Dörr, Oliver
  33. Al-Hariri, Abdulaziz
  34. Boening, Ursula
  35. Faßbender, Sven
  36. Funk, Charlotte
  37. Haas, Moritz
  38. Hamm, Catharina
  39. Hofmann, Felix
  40. Karatolios, Konstantinos
  41. Körschgen, Tore
  42. Michalek, Kerstin
  43. Schauberger, Shari
  44. Neumann, Sylvana
  45. Runde, Thorsten
  46. Rutsatz, Wiebke
  47. Stanisch, Michael
  48. Schifferings, Peter
  49. Schneider, Eberhard
  50. Weferling, Maren

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1000 Titel
  • Impact of the COVID-19 pandemic on cardiovascular mortality and catherization activity during the lockdown in central Germany: an observational study
1000 Autor/in
  1. Nef, Holger M. |
  2. Elsässer, Albrecht |
  3. Möllmann, Helge |
  4. Abdel-Hadi, Mohammed |
  5. Bauer, Timm |
  6. Brück, Martin |
  7. Eggebrecht, Holger |
  8. Ehrlich, Joachim R. |
  9. Ferrari, Markus W. |
  10. Fichtlscherer, Stephan |
  11. Hink, Ulrich |
  12. Hölschermann, Hans |
  13. Kacapor, Rifat |
  14. Koeth, Oliver |
  15. Korboukov, Serguei |
  16. Lamparter, Steffen |
  17. Laspoulas, Alexander J. |
  18. Lehmann, Ralf |
  19. Liebetrau, Christoph |
  20. Plücker, Tobias |
  21. Pons-Kühnemann, Jörn |
  22. Schächinger, Volker |
  23. Schieffer, Bernhard |
  24. Schott, Peter |
  25. Schulze, Matthias |
  26. Teupe, Claudius |
  27. Vasa-Nicotera, Mariuca |
  28. Weber, Michael |
  29. Weinbrenner, Christoph |
  30. Werner, Gerald |
  31. Hamm, Christian W. |
  32. Dörr, Oliver |
  33. Al-Hariri, Abdulaziz |
  34. Boening, Ursula |
  35. Faßbender, Sven |
  36. Funk, Charlotte |
  37. Haas, Moritz |
  38. Hamm, Catharina |
  39. Hofmann, Felix |
  40. Karatolios, Konstantinos |
  41. Körschgen, Tore |
  42. Michalek, Kerstin |
  43. Schauberger, Shari |
  44. Neumann, Sylvana |
  45. Runde, Thorsten |
  46. Rutsatz, Wiebke |
  47. Stanisch, Michael |
  48. Schifferings, Peter |
  49. Schneider, Eberhard |
  50. Weferling, Maren |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-11-21
1000 Erschienen in
1000 Quellenangabe
  • 110(2):292-301
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00392-020-01780-0 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680078/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Aims!#!During the COVID-19 pandemic, hospital admissions for cardiac care have declined. However, effects on mortality are unclear. Thus, we sought to evaluate the impact of the lockdown period in central Germany on overall and cardiovascular deaths. Simultaneously we looked at catheterization activities in the same region.!##!Methods and results!#!Data from 22 of 24 public health-authorities in central Germany were aggregated during the pandemic related lockdown period and compared to the same time period in 2019. Information on the total number of deaths and causes of death, including cardiovascular mortality, were collected. Additionally, we compared rates of hospitalization (n = 5178) for chronic coronary syndrome (CCS), acute coronary syndrome (ACS), and out of hospital cardiac arrest (OHCA) in 26 hospitals in this area. Data on 5,984 deaths occurring between March 23, 2020 and April 26, 2020 were evaluated. In comparison to the reference non-pandemic period in 2019 (deaths: n = 5832), there was a non-significant increase in all-cause mortality of 2.6% [incidence rate ratio (IRR) 1.03, 95% confidence interval (CI) 0.99-1.06; p = 0.16]. Cardiovascular and cardiac mortality increased significantly by 7.6% (IRR 1.08, 95%-CI 1.01-1.14; p = 0.02) and by 11.8% (IRR 1.12, 95%-CI 1.05-1.19; p < 0.001), respectively. During the same period, our data revealed a drop in cardiac catherization procedures.!##!Conclusion!#!During the COVID-19-related lockdown a significant increase in cardiovascular mortality was observed in central Germany, whereas catherization activities were reduced. The mechanisms underlying both of these observations should be investigated further in order to better understand the effects of a pandemic-related lockdown and social-distancing restrictions on cardiovascular care and mortality.
1000 Sacherschließung
gnd 1206347392 COVID-19
lokal Aged [MeSH]
lokal Hospital Mortality/trends [MeSH]
lokal Cardiovascular Diseases/diagnosis [MeSH]
lokal Cardiovascular mortality
lokal Risk Factors [MeSH]
lokal Cardiac Catheterization/adverse effects [MeSH]
lokal Acute coronary syndrome
lokal Male [MeSH]
lokal COVID-19 [MeSH]
lokal Cardiac Catheterization/trends [MeSH]
lokal Cardiovascular Diseases/mortality [MeSH]
lokal Female [MeSH]
lokal Chronic coronary syndrome
lokal Cardiac Catheterization/mortality [MeSH]
lokal Humans [MeSH]
lokal SARS-CoV2 pandemic
lokal Percutaneous Coronary Intervention/trends [MeSH]
lokal Middle Aged [MeSH]
lokal COVID-19
lokal Time Factors [MeSH]
lokal Percutaneous Coronary Intervention/adverse effects [MeSH]
lokal Cause of Death/trends [MeSH]
lokal Germany [MeSH]
lokal Original Paper
lokal Cardiovascular Diseases/therapy [MeSH]
lokal Percutaneous Coronary Intervention/mortality [MeSH]
lokal Hospitalization/trends [MeSH]
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