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1000 Titel
  • The Frozen Elephant Technique Using a Novel Hybrid Prosthesis for Extensive Aortic Arch Disease: A Multicentre Study
1000 Autor/in
  1. El-Sayed Ahmad, Ali |
  2. Silaschi, Miriam |
  3. Borger, Michael |
  4. Seidiramool, Vahid |
  5. Hamiko, Marwan |
  6. Leontyev, Sergey |
  7. Zierer, Andreas |
  8. Doss, Mirko |
  9. Etz, Christian D. |
  10. Benedikt, Peter |
  11. Bramlage, Peter |
  12. Bakhtiary, Farhad |
1000 Verlag
  • Springer Healthcare
1000 Erscheinungsjahr 2023
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2023-01-12
1000 Erschienen in
1000 Quellenangabe
  • 40(3):1104-1113
1000 Copyrightjahr
  • 2023
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s12325-022-02418-5 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988725/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Introduction!#!The frozen elephant trunk technique (FET) has become routine for aortic arch and descending aortic repair. New hybrid prosthesis models are constantly being developed to increase effectiveness and durability of aortic repair. Recently, concerns were raised regarding increased post-operative bleeding using a new-generation hybrid prosthesis (E-vita!##!Methods!#!All patients undergoing aortic surgery at five European centres using the E-vita OPEN NEO from 2020 to 2022 were included (n = 22). The primary endpoint was the amount of chest drain fluid after 24 h and re-thoracotomy rate for bleeding.!##!Results!#!Median patient age was 62.5 ± 12.6 years, 50.0% (11/22 patients) were female and 27.3% (6/22) of procedures were re-operative cardiac surgeries. Aortic dissection was present in 54.5% (12/22). The median cardiopulmonary bypass time was 148 min and ischaemia time was 84 min. Mortality at 30 days was 4.5% (1/22) and the stroke rate was 18.2% (4/22). The rate of re-thoracotomy for bleeding was 4.5% (1/22) with a median amount of chest drain fluid within 24 h of 569 (IQR 338-910) ml. There were no device-associated adverse events.!##!Conclusions!#!Use of this new-generation hybrid prosthesis for FET was safe and effective. Patient follow-up was largely uneventful given the extent of the procedures performed. In particular, bleeding events were uncommon in this cohort of patients comprising many aortic dissections and re-operative procedures. No increase in oozing was observed.
1000 Sacherschließung
lokal Female [MeSH]
lokal Aged [MeSH]
lokal Aortic Dissection/surgery [MeSH]
lokal Humans [MeSH]
lokal Treatment Outcome [MeSH]
lokal Aortic surgery
lokal Retrospective Studies [MeSH]
lokal Middle Aged [MeSH]
lokal Blood Vessel Prosthesis Implantation/adverse effects [MeSH]
lokal Aorta, Thoracic/surgery [MeSH]
lokal Frozen elephant trunk
lokal Blood Vessel Prosthesis [MeSH]
lokal Male [MeSH]
lokal Hybrid aortic repair
lokal Aorta, Thoracic/diagnostic imaging [MeSH]
lokal Original Research
lokal Aortic prosthesis
lokal Blood Vessel Prosthesis Implantation/methods [MeSH]
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