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1000 Titel
  • Right-to-left-shunts in patients scheduled for neurosurgical intervention in semi-sitting position – a literature review based on two case scenarios
1000 Autor/in
  1. Nikolic, Marina |
  2. Eisner, C. |
  3. Neumann, J. O. |
  4. Haux, D. |
  5. Krieg, S. M. |
  6. Wielpütz, M. O. |
  7. Weigand, M. A. |
  8. Tochtermann, U. |
  9. Fischer, Dania |
1000 Verlag BioMed Central
1000 Erscheinungsjahr 2024
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-10-16
1000 Erschienen in
1000 Quellenangabe
  • 24(1):375
1000 Copyrightjahr
  • 2024
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12871-024-02757-6 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11481392/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>Neurosurgery performed in the semi-sitting position provides advantages for certain procedures. However, this approach is associated with potential complications, particularly venous air embolism. Due to typically negative venous pressure at the wound site, air can be drawn into the veins. This risk is especially high in patients presenting with an intra- or extracardiac right-to-left-shunt. Transoesophageal echocardiography can be used to detect a patent foramen ovale or other possible pulmonary-systemic shunt before placing the patient in the sitting position.</jats:p> </jats:sec><jats:sec> <jats:title>Case presentation</jats:title> <jats:p>In this report, we present two young patients undergoing scheduled microsurgical vestibular schwannoma removal in a semi-sitting position who were diagnosed with congenital heart defects during routine perioperative assessment to detect possible intracardiac right-to-left shunts, using pre- and intraoperative transesophageal echocardiography (TEE) and additionally conducting an agitated saline bubble study under Valsalva manoeuvre. Patient A was diagnosed with a persistent left superior vena cava and Patient B with an unroofed coronary sinus (UCS). These findings confronted the anesthesiological and surgical teams with difficult individual decisions regarding further perioperative management.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusions</jats:title> <jats:p>Perioperative transesophageal echocardiography is a diagnostic tool to both detect intraoperative position-related air embolisms and to rule out intracardiac right-to-left shunts, e.g. a patent foramen ovale, in order to decide for or against a (semi-)sitting position. Depending on the surgical circumstances a semi-sitting positioning of patients presenting with an intracardiac right-to-left-shunt, e.g. a PFO, can be feasible in individual cases if there is an implemented therapeutic algorithm to immediately terminate significant venous air entry. However, since certain other intra- or extracardiac right-to-left-shunts, such as here presented PLSVC or UCS, are rare, there is no definitive way of estimating the amount of entered air through detected shunts or anomalous vessels. Therefore, it is recommended to avoid a (semi-)sitting position in favour of a lateral or prone position for a patient undergoing intracranial surgery, once the perioperative TEE shows air bubbles in the left atrium or ventricle whose origins cannot be defined solely through TEE for certain in order to ensure patient safety by minimizing the risk of intraoperative paradoxical air embolisms.</jats:p> </jats:sec>
1000 Sacherschließung
lokal Female [MeSH]
lokal Adult [MeSH]
lokal Humans [MeSH]
lokal Embolism, Air/diagnostic imaging [MeSH]
lokal Neuroma, Acoustic/surgery [MeSH]
lokal Patent foramen ovale
lokal Heart Defects, Congenital/surgery [MeSH]
lokal Right-to-left-shunt
lokal Neurosurgical Procedures/methods [MeSH]
lokal Male [MeSH]
lokal Embolism, Air/etiology [MeSH]
lokal Patient Positioning/methods [MeSH]
lokal Embolism, Air/prevention
lokal Sitting Position [MeSH]
lokal Echocardiography, Transesophageal/methods [MeSH]
lokal Semi-sitting position
lokal Perioperative TEE
lokal Case Report
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/Tmlrb2xpYywgTWFyaW5h|https://frl.publisso.de/adhoc/uri/RWlzbmVyLCBDLg==|https://frl.publisso.de/adhoc/uri/TmV1bWFubiwgSi4gTy4=|https://frl.publisso.de/adhoc/uri/SGF1eCwgRC4=|https://frl.publisso.de/adhoc/uri/S3JpZWcsIFMuIE0u|https://frl.publisso.de/adhoc/uri/V2llbHDDvHR6LCBNLiBPLg==|https://frl.publisso.de/adhoc/uri/V2VpZ2FuZCwgTS4gQS4=|https://frl.publisso.de/adhoc/uri/VG9jaHRlcm1hbm4sIFUu|https://frl.publisso.de/adhoc/uri/RmlzY2hlciwgRGFuaWE=
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  1. Medizinische Fakultät Heidelberg der Universität Heidelberg |
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    1000 Förderer Medizinische Fakultät Heidelberg der Universität Heidelberg |
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1000 Erstellt am 2025-07-05T03:54:32.223+0200
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1000 Zuletzt bearbeitet 2025-08-15T19:45:23.314+0200
1000 Objekt bearb. Fri Aug 15 19:45:23 CEST 2025
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