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CTLA4 promoter methylation predicts response and progression-free survival in stage IV melanoma treated with anti-CTLA-4 immunotherapy (ipilimumab)

2020 . Fietz, Simon | Zarbl, Romina | Niebel, Dennis | Posch, Christian | Brossart, Peter | Gielen, Gerrit H. | Strieth, Sebastian | Pietsch, Torsten | Kristiansen, Glen | Bootz, Friedrich | Landsberg, Jennifer | Dietrich, Dimo

Multi-layered epigenetic regulation of IRS2 expression in the liver of obese individuals with type 2 diabetes

2020 . Krause, Christin | Geißler, Cathleen | Tackenberg, Heidi | El Gammal, Alexander T. | Wolter, Stefan | Spranger, Joachim | Mann, Oliver | Lehnert, Hendrik | Kirchner, Henriette

Whole blood DNA methylation aging markers predict colorectal cancer survival: a prospective cohort study

2020 . Gao, Xin | Zhang, Yan | Boakye, Daniel | Li, Xiangwei | Chang-Claude, Jenny | Hoffmeister, Michael | Brenner, Hermann

Genetically programmed changes in transcription of the novel progranulin regulator

2020 . Keller, Maria | Gebhardt, Claudia | Huth, Sandra | Schleinitz, Dorit | Heyne, Henrike | Scholz, Markus | Stumvoll, Michael | Böttcher, Yvonne | Tönjes, Anke | Kovacs, Peter

RASSF10 is frequently epigenetically inactivated in kidney cancer and its knockout promotes neoplasia in cancer prone mice

2020 . , Antje | Woods, Michelle L. | Küster, Miriam M. | Walesch, Sara K. | Braun, Thomas | Boettger, Thomas | Dammann, Reinhard H.

Downregulation of SFRP1 is a protumorigenic event in hepatoblastoma and correlates with beta-catenin mutations

2020 . Regel, Ivonne | Eichenmüller, Melanie | Mahajan, Ujjwal Mukund | Hagl, Beate | Benitz, Simone | Häberle, Beate | Vokuhl, Christian | von Schweinitz, Dietrich | Kappler, Roland

Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis

PRDM8 reveals aberrant DNA methylation in aging syndromes and is relevant for hematopoietic and neuronal differentiation

2020 . Cypris, Olivia | Eipel, Monika | Franzen, Julia | Rösseler, Corinna | Tharmapalan, Vithurithra | Kuo, Chao-Chung | Vieri, Margherita | Nikolić, Miloš | Kirschner, Martin | Brümmendorf, Tim H. | Zenke, Martin | Lampert, Angelika | Beier, Fabian | Wagner, Wolfgang

DNA methylation signature in blood mirrors successful weight-loss during lifestyle interventions: the CENTRAL trial

MeCP2 gates spatial learning-induced alternative splicing events in the mouse hippocampus

2020 . Vilhena Catarino Brito, David | Gulmez Karaca, Kubra | Kupke, Janina | Frank, Lukas | Oliveira, Ana M.M.