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Bortezomib-releasing silica-collagen xerogels for local treatment of osteolytic bone- and minimal residual disease in multiple myeloma

Nanoformulation of dasatinib cannot overcome therapy resistance of pancreatic cancer cells with low LYN kinase expression

2024 . Kaul, Marilyn | Sanin, Ahmed Y. | Shi, Wenjie | Janiak, Christoph | Kahlert, Ulf Dietrich

Targeting the glutamine metabolism to suppress cell proliferation in mesenchymal docetaxel-resistant prostate cancer

2024 . Beier, Alicia-Marie K. | Ebersbach, Celina | Siciliano, Tiziana | Scholze, Jana | Hofmann, Jörg | Hönscheid, Pia | Baretton, Gustavo B. | Woods, Kevin | Guezguez, Borhane | Dubrovska, Anna | Markowitsch, Sascha D. | Thomas, Christian | Puhr, Martin | Erb, Holger

Anti-tumor effects of tirbanibulin in squamous cell carcinoma cells are mediated via disruption of tubulin-polymerization

2024 . DeTemple, Viola K. | Walter, Antje | Bredemeier-Rasche, Sabine | Gutzmer, Ralf | Schaper-Gerhardt, Katrin

Drug prioritization identifies panobinostat as a tailored treatment element for patients with metastatic hepatoblastoma

2024 . Demir, Salih | Hotes, Alina | Schmid, Tanja | Cairo, Stefano | Indersie, Emilie | Pisano, Claudio | Hiyama, Eiso | Hishiki, Tomoro | Vokuhl, Christian | Branchereau, Sophie | Brock, Penelope | Schmid, Irene | Zsiros, József | Kappler, Roland

Antineoplastic therapy affects the in vitro phenotype and functionality of healthy human bone marrow-derived mesenchymal stromal cells

2024 . Scherer, Bo | Bogun, Lucienne | Koch, Annemarie | Jäger, Paul | Maus, Uwe | Schmitt, Laura | Krings, Karina S. | Wesselborg, Sebastian | Haas, Rainer | Schroeder, Thomas | Geyh, Stefanie

A spheroid whole mount drug testing pipeline with machine-learning based image analysis identifies cell-type specific differences in drug efficacy on a single-cell level

2024 . Vitacolonna, Mario | Bruch, Roman | Schneider, Richard | Jabs, Julia | Hafner, Mathias | Reischl, Markus | Rudolf, Rüdiger

Complexation of histone deacetylase inhibitor belinostat to Cu(II) prevents premature metabolic inactivation in vitro and demonstrates potent anti-cancer activity in vitro and ex vivo in colon cancer

Strong apoptotic response of testis tumor cells following cisplatin treatment

2023 . Köberle, Beate | Usanova, Svetlana | Piee-Staffa, Andrea | Heinicke, Ulrike | Clauss, Philipp | Brozovic, Anamaria | Kaina, Bernd

Vincetoxicum arnottianum modulates motility features and metastatic marker expression in pediatric rhabdomyosarcoma by stabilizing the actin cytoskeleton

2021 . Adamus, Anna | Ali, Iftikhar | Vasileiadis, Vasileios | Al-Hileh, Luai | Lisec, Jan | Frank, Marcus | Seitz, Guido | Engel, Nadja

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