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Neurodegenerative phosphoprotein signaling landscape in models of SCA3

2021 . Sowa, Anna | Popova, Taissia G. | Harmuth, Tina | Weber, Jonasz Jeremiasz | Pereira Sena, Priscila | Schmidt, Jana | Hübener-Schmid, Jeannette | Schmidt, Thorsten

Human alpha-synuclein overexpressing MBP29 mice mimic functional and structural hallmarks of the cerebellar subtype of multiple system atrophy

2021 . Mészáros, Lisa | Riemenschneider, Markus J. | Gassner, Heiko | Marxreiter, Franz | von Hörsten, Stephan | Hoffmann, Alana | Schlachetzki, Johannes

Astrocyte-specific expression of interleukin 23 leads to an aggravated phenotype and enhanced inflammatory response with B cell accumulation in the EAE model

2021 . Nitsch, Louisa | Petzinna, Simon | Zimmermann, Julian | Schneider, Linda | Krauthausen, Marius | Heneka, Michael T. | Getts, Daniel R. | Becker, Albert | Müller, Marcus

Interleukin-10 improves stroke outcome by controlling the detrimental Interleukin-17A response

Overexpression of Lin28A in neural progenitor cells in vivo does not lead to brain tumor formation but results in reduced spine density

2021 . Middelkamp, Maximilian | Ruck, Lisa | Krisp, Christoph | Sumisławski, Piotr | Mohammadi, Behnam | Dottermusch, Matthias | Meister, Valerie | Küster, Lukas | Schlüter, Hartmut | Windhorst, Sabine | Neumann, Julia E.

Prominent microglial inclusions in transgenic mouse models of α-synucleinopathy that are distinct from neuronal lesions

Targeting isoaspartate-modified Aβ rescues behavioral deficits in transgenic mice with Alzheimer’s disease-like pathology

Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases

Acute brain injuries trigger microglia as an additional source of the proteoglycan NG2

2020 . Huang, Wenhui | Bai, Xianshu | Meyer, Erika | Scheller, Anja