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Deciphering the immunosuppressive tumor microenvironment in ALK- and EGFR-positive lung adenocarcinoma

Small cell lung cancer stem cells display mesenchymal properties and exploit immune checkpoint pathways in activated cytotoxic T lymphocytes

2021 . Kursunel, M. Alper | Taskiran, Ekim Z. | Tavukcuoglu, Ece | Yanik, Hamdullah | Demirag, Funda | Karaosmanoglu, Beren | Ozbay, Feyza Gul | Uner, Aysegul | Esendagli, Dorina | Kizilgoz, Derya | Yilmaz, Ulku | Esendagli, Gunes

Systemic but not MDSC-specific IRF4 deficiency promotes an immunosuppressed tumor microenvironment in a murine pancreatic cancer model

2020 . Metzger, Philipp | Kirchleitner, Sabrina Viktoria | Boehmer, Daniel | Hörth, Christine | Eisele-Metzger, Angelika | Ormanns, Steffen | Gunzer, Matthias | Lech, Maciej | Lauber, Kirsten | Endres, Stefan | Duewell, Peter | Schnurr, Max | König, Lars

Cancer testis antigen Cyclin A1 harbors several HLA-A*02:01-restricted T cell epitopes, which are presented and recognized in vivo

2020 . Teck, Anja Tatjana | Urban, Sabrina | Quass, Petra | Nelde, Annika | Schuster, Heiko | Letsch, Anne | Busse, Antonia | Walz, Juliane Sarah | Keilholz, Ulrich | Ochsenreither, Sebastian

BRAF and MEK inhibition in melanoma patients enables reprogramming of tumor infiltrating lymphocytes

2020 . Peiffer, Lukas | Farahpour, Farnoush | Sriram, Ashwin | Spassova, Ivelina | Hoffmann, Daniel | Kubat, Linda | Stoitzner, Patrizia | Gambichler, Thilo | Sucker, Antje | Ugurel, Selma | Schadendorf, Dirk | Becker, Jürgen

Adenosine-producing regulatory B cells in head and neck cancer

2020 . Jeske, Sandra S. | Brand, Matthias | Ziebart, Andreas | Laban, Simon | Doescher, Johannes | Greve, Jens | Jackson, Edwin K. | Hoffmann, Thomas K. | Brunner, Cornelia | Schuler, Patrick J.