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Toxicokinetics of U-47700, tramadol, and their main metabolites in pigs following intravenous administration: is a multiple species allometric scaling approach useful for the extrapolation of toxicokinetic parameters to humans?

2021 . Nordmeier, Frederike | Sihinevich, Iryna | Doerr, Adrian A. | Walle, Nadja | Laschke, Matthias W. | Lehr, Thorsten | Menger, Michael D. | Schmidt, Peter H. | Meyer, Markus R. | Schaefer, Nadine

Comprehensive Parent–Metabolite PBPK/PD Modeling Insights into Nicotine Replacement Therapy Strategies

2020 . Kovar, Lukas | Selzer, Dominik | Britz, Hannah | Benowitz, Neal | St. Helen, Gideon | Kohl, Yvonne | Bals, Robert | Lehr, Thorsten

Physiologically Based Pharmacokinetic Models of Probenecid and Furosemide to Predict Transporter Mediated Drug-Drug Interactions

2020 . Britz, Hannah | Hanke, Nina | Taub, Mitchell E. | Wang, Ting | Prasad, Bhagwat | Fernandez, Éric | Stopfer, Peter | Nock, Valerie | Lehr, Thorsten

Effective Removal of Dabigatran by Idarucizumab or Hemodialysis: A Physiologically Based Pharmacokinetic Modeling Analysis

2020 . Fuhr, Laura Maria | Hanke, Nina | Meibohm, Bernd | Lehr, Thorsten

A Comprehensive Whole-Body Physiologically Based Pharmacokinetic Drug–Drug–Gene Interaction Model of Metformin and Cimetidine in Healthy Adults and Renally Impaired Individuals

2020 . Hanke, Nina | Türk, Denise | Selzer, Dominik | Ishiguro, Naoki | Ebner, Thomas | Wiebe, Sabrina | Müller, Fabian | Stopfer, Peter | Nock, Valerie | Lehr, Thorsten

Population nutrikinetics of green tea extract

2018 . Scholl, Catharina | Lepper, Anna | Lehr, Thorsten | Hanke, Nina | Schneider, Luise, Katharina | Brockmüller, Jürgen | Seufferlein, Thomas | Stingl, Julia