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Individualised dosing of antibiotics in ICU patients: timing, target and model selection matter

2023 . Liebchen, Uwe | Briegel, Josef | Brinkmann, Alexander | Frey, Otto | Wicha, Sebastian G.

Towards model-informed precision dosing of piperacillin: multicenter systematic external evaluation of pharmacokinetic models in critically ill adults with a focus on Bayesian forecasting

Pharmacokinetics and Pharmacodynamics of Tedizolid

2022 . Iqbal, Khalid | Milioudi, Aliki | Wicha, Sebastian G.

Inferring pulmonary exposure based on clinical PK data: accuracy and precision of model-based deconvolution methods

2021 . Himstedt, Anneke | Borghardt, Jens Markus | Wicha, Sebastian G.

Evaluation of the Robustness of Therapeutic Drug Monitoring Coupled with Bayesian Forecasting of Busulfan with Regard to Inaccurate Documentation

2021 . Dadkhah, Adrin | Alihodzic, Dzenefa | Broeker, Astrid | Kröger, Nicolaus | Langebrake, Claudia | Wicha, Sebastian G.

Population Pharmacokinetics of PEGylated Asparaginase in Children with Acute Lymphoblastic Leukemia: Treatment Phase Dependency and Predictivity in Case of Missing Data

2021 . Würthwein, Gudrun | Lanvers-Kaminsky, Claudia | Siebel, Christian | Gerss, Joachim | Möricke, Anja | Zimmermann, Martin | Stary, Jan | Smíšek, Petr | Schrappe, Martin | RIZZARI, Carmelo | Zucchetti, Massimo | Hempel, Georg | Wicha, Sebastian G. | Boos, Joachim

An Integrated Dialysis Pharmacometric (IDP) Model to Evaluate the Pharmacokinetics in Patients Undergoing Renal Replacement Therapy

2020 . Broeker, Astrid | Vossen, Matthias G. | Thalhammer, Florian | Wallis, Steven C. | Lipman, Jeffrey | Roberts, Jason A. | Wicha, Sebastian G.

Stability studies with tigecycline in bacterial growth medium and impact of stabilizing agents

2020 . Amann, Lisa F. | Vicente, Emilia Ruda | Rathke, Mareike | Broeker, Astrid | Riedner, Maria | Wicha, Sebastian G.

Assessing parameter uncertainty in small-n pharmacometric analyses: value of the log-likelihood profiling-based sampling importance resampling (LLP-SIR) technique

2020 . Broeker, Astrid | Wicha, Sebastian G.

Pharmacokinetics of tigecycline in critically ill patients with liver failure defined by maximal liver function capacity test (LiMAx)

2020 . Alraish, Rawan | Wicha, Sebastian G. | Frey, Otto R. | Roehr, Anka C. | Pratschke, Johann | Stockmann, Martin | Wuensch, Tilo | Kaffarnik, Magnus