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Altered translation elongation contributes to key hallmarks of aging in the killifish brain

Reducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans

Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during aging

2023 . Schädel, Patrick | Czapka, Anna | Gebert, Nadja | Jacobsen, Ilse D. | Ori, Alessandro | Werz, Oliver

Organelle dysfunction and its contribution to metabolic impairments in aging and age-related diseases

2022 . Heiby, Julia C. | Ori, Alessandro

Conserved exchange of paralog proteins during neuronal differentiation

2022 . Di Fraia, Domenico | Anitei, Mihaela | Mackmull, Marie-Therese | Parca, Luca | Behrendt, Laura | Andres-Pons, Amparo | Gilmour, Darren | Helmer-Citterich, Manuela | Kaether, Christoph | Beck, Martin | Ori, Alessandro

HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration

2021 . Tapias, Alicia | Lázaro, David | Yin, Bo-Kun | Rasa, Seyed Mohammad Mahdi | Krepelova, Anna | Kelmer Sacramento, Erika | Grigaravicius, Paulius | Koch, Philipp | Kirkpatrick, Joanna | Ori, Alessandro | Neri, Francesco | wang, zhao-qi

Mapping protein carboxymethylation sites provides insights into their role in proteostasis and cell proliferation

2021 . Di Sanzo, Simone | Spengler, Katrin | Leheis, Anja | Kirkpatrick, Joanna | Rändler, Theresa | Baldensperger, Tim | Dau, Therese | Henning, Christian | Parca, Luca | Marx, Christian | Wang, Zhao-Qi | Glomb, Marcus A. | Ori, Alessandro | Heller, Regine

ATR regulates neuronal activity by modulating presynaptic firing

2021 . Kirtay, Murat | Sell, Josefine | Marx, Christian | Haselmann, Holger | Ceanga, Mihai | Zhou, Zhong-Wei | Rahmati, Vahid | Kirkpatrick, Joanna | Buder, Katrin | Grigaravicius, Paulius | Ori, Alessandro | Geis, Christian | wang, zhao-qi

Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation

Quantifying compartment‐associated variations of protein abundance in proteomics data

2018 . Parca, Luca | Beck, Martin | Bork, Peer | Ori, Alessandro

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