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ARTS and small-molecule ARTS mimetics upregulate p53 levels by promoting the degradation of XIAP

2024 . Abbas, Ruqaia | Hartmann, Oliver | Asiss, Dorin Theodora | Abbas, Rabab | Kagan, Julia | Kim, Hyoung-Tae | Oren, Moshe | Diefenbacher, Markus | Orian, Amir | Larisch, Sarit

The caspase-inhibitor Emricasan efficiently counteracts cisplatin- and neomycin-induced cytotoxicity in cochlear cells

2024 . Nassauer, Larissa | Schott, Juliane Wilhelmine | Harre, Jennifer | Warnecke, Athanasia | Morgan, Michael | Galla, Melanie | Schambach, Axel

Microarray-based detection and expression analysis of drug resistance in an animal model of peritoneal metastasis from colon cancer

2024 . Yagublu, Vugar | Bayramov, Bayram | Reissfelder, Christoph | Hajibabazade, Javahir | Abdulrahimli, Shalala | Keese, Michael

Cytotoxic impact of nicotine products on periodontal ligament cells

2024 . Wiesmann-Imilowski, Nadine | Becker, Philipp | Gielisch, Matthias W. | Ziebolz, Dirk | Vermehren, Franziska | Bitschnau, Marian | Langguth, Nils | Brieger, Jürgen | Deschner, James | Kämmerer, Peer W.

Osthole ameliorates wear particle-induced osteogenic impairment by mitigating endoplasmic reticulum stress via PERK signaling cascade

2024 . Yu, Xin | Jiang, Juan | Li, Cheng | Wang, Yang | Ren, Zhengrong | Hu, Jianlun | Yuan, Tao | Wu, Yongjie | Wang, Dongsheng | Sun, Ziying | Wu, Qi | Chen, Bin | Fang, Peng | Ding, Hao | Meng, Jia | Jiang, Hui | Zhao, Jianning | Bao, Nirong

Anti-tumor effects of tirbanibulin in squamous cell carcinoma cells are mediated via disruption of tubulin-polymerization

2024 . DeTemple, Viola K. | Walter, Antje | Bredemeier-Rasche, Sabine | Gutzmer, Ralf | Schaper-Gerhardt, Katrin

A spheroid whole mount drug testing pipeline with machine-learning based image analysis identifies cell-type specific differences in drug efficacy on a single-cell level

2024 . Vitacolonna, Mario | Bruch, Roman | Schneider, Richard | Jabs, Julia | Hafner, Mathias | Reischl, Markus | Rudolf, Rüdiger

Complexation of histone deacetylase inhibitor belinostat to Cu(II) prevents premature metabolic inactivation in vitro and demonstrates potent anti-cancer activity in vitro and ex vivo in colon cancer

Neuroprotective and antioxidative effects of pioglitazone in brain tissue adjacent to the ischemic core are mediated by PI3K/Akt and Nrf2/ARE pathways

2021 . Zhao, Yi | Lützen, Ulf | Gohlke, Peter | Jiang, Ping | Herdegen, Thomas | Culman, Juraj

Chronic senescent human mesenchymal stem cells as possible contributor to the wound healing disorder after exposure to the alkylating agent sulfur mustard

2021 . Rothmiller, Simone | Jäger, Niklas | Meier, Nicole | Meyer, Thimo | Neu, Adrian | Steinritz, Dirk | Thiermann, Horst | Scherer, Michael | Rummel, Christoph | Mangerich, Aswin | Bürkle, Alexander | Schmidt, Annette

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