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The missing link: ARID1B non-truncating variants causing Coffin-Siris syndrome due to protein aggregation

2024 . Bosch, Elisabeth | Güse, Esther | Kirchner, Philipp | Winterpacht, Andreas | Walther, Mona | Alders, Marielle | Kerkhof, Jennifer | Ekici, Arif B. | Sticht, Heinrich | Sadikovic, Bekim | Reis, André | Vasileiou, Georgia

Hybrid Molecular and Functional Micro-CT Imaging Reveals Increased Myocardial Apoptosis Preceding Cardiac Failure in Progeroid Ercc1 Mice

ASPM promotes ATR-CHK1 activation and stabilizes stalled replication forks in response to replication stress

2022 . WU, Xingxuan | Xu, Shibin | Wang, Peipei | wang, zhao-qi | Chen, Hongxiang | Xu, Xingzhi | PENG, BIN

Erythropoietin Abrogates Post-Ischemic Activation of the NLRP3, NLRC4, and AIM2 Inflammasomes in Microglia/Macrophages in a TAK1-Dependent Manner

2021 . Heinisch, Ole | Zeyen, Thomas | Goldmann, Tobias | Prinz, Marco | Huber, Michael | Jung, Jennifer | Arik, Eren | Habib, Shahin | Slowik, Alexander | Reich, Arno | Schulz, Jörg B. | Habib, Pardes

Nesfatin-1 decreases the motivational and rewarding value of food

NBS1 interacts with Notch signaling in neuronal homeostasis

2020 . Zhou, Zhong-Wei | Kirtay, Murat | Schneble, Nadine | Yakoub, George | Ding, Mingmei | Rüdiger, Tina | Siniuk, Kanstantsin | Lu, Ruiqing | Jiang, Yi-Nan | Li, Tangliang | Kaether, Christoph | Barzilai, Ari | wang, zhao-qi

Antibody against TDP-43 phosphorylated at serine 375 suggests conformational differences of TDP-43 aggregates among FTLD–TDP subtypes

2020 . Neumann, Manuela | Frick, Petra | Paron, Francesca | Kosten, Jonas | Buratti, Emanuele | Mackenzie, Ian R.

Histone deacetylase inhibitors dysregulate DNA repair proteins and antagonize metastasis-associated processes

2020 . Kiweler, Nicole | Wünsch, Désirée | Wirth, Matthias | Mahendrarajah, Nisintha | Schneider, Günter | Stauber, Roland H. | Brenner, Walburgis | Butter, Falk | Krämer, Oliver

ZBTB7A prevents RUNX1-RUNX1T1-dependent clonal expansion of human hematopoietic stem and progenitor cells

Unraveling Molecular Mechanisms of THAP1 Missense Mutations in DYT6 Dystonia

2020 . Cheng, Fubo | Walter, Michael | Wassouf, Zinah | Hentrich, Thomas | Casadei, Nicolas | Schulze-Hentrich, Julia | Barbuti, Peter | Krueger, Rejko | Riess, Olaf | Grundmann-Hauser, Kathrin | Ott, Thomas

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