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Identification of potential novel drug resistance mechanisms by genomic and transcriptomic profiling of colon cancer cells with p53 deletion

2021 . Kadioglu, Onat | Saeed, Mohamed | Mahmoud, Nuha | Azawi, Shaymaa | Mrasek, Kristin | Liehr, Thomas | Efferth, Thomas

Network pharmacology of triptolide in cancer cells: implications for transcription factor binding

2021 . Seo, Ean-Jeong | Dawood, Mona | Hult, Annika K. | Olsson, Martin L. | Efferth, Thomas

Selection of safe artemisinin derivatives using a machine learning-based cardiotoxicity platform and in vitro and in vivo validation

2021 . Kadioglu, Onat | Klauck, Sabine M. | Fleischer, Edmond | Shan, Letian | Efferth, Thomas

A novel ligand of the translationally controlled tumor protein (TCTP) identified by virtual drug screening for cancer differentiation therapy

2021 . Fischer, Nicolas | Seo, Ean-Jeong | Abdelfatah, Sara | Fleischer, Edmond | Klinger, Anette | Efferth, Thomas

Identification and characterization of deschloro-chlorothricin obtained from a large natural product library targeting aurora A kinase in multiple myeloma

2020 . Özenver, Nadire | Abdelfatah, Sara | Klinger, Anette | Fleischer, Edmond | Efferth, Thomas

Drug repurposing using transcriptome sequencing and virtual drug screening in a patient with glioblastoma

2020 . Saeed, Mohamed E. M. | Kadioglu, Onat | Greten, Henry Johannes | Yildirim, Adem | Mayr, Katharina | Wenz, Frederik | Giordano, Frank A. | Efferth, Thomas