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In vitro to in vivo acetaminophen hepatotoxicity extrapolation using classical schemes, pharmacodynamic models and a multiscale spatial-temporal liver twin

2023 . Dichamp, Jules | Celliere, Géraldine | Ghallab, Ahmed | hassan, reham | Boissier, Noemie | Hofmann, Ute | Reinders, Joerg | Sezgin, Selahaddin | Zuehlke, Sebastian | Hengstler, Jan | Drasdo, Dirk

Automated Detection of Portal Fields and Central Veins in Whole-Slide Images of Liver Tissue

2022 . Budelmann, Daniel | Laue, Hendrik | Weiss, Nick | Dahmen, Uta | D’Alessandro, Lorenza A. | Biermayer, Ina | Klingmüller, Ursula | Ghallab, Ahmed | Hassan, Reham | Begher-Tibbe, Brigitte | Hengstler, Jan | Schwen, Lars Ole

Comparative histological analysis of the skin for forensic investigation of some animal species

2022 . MOHAMMED, ELSAYED SEDDEK IBRAHEM | Madkour, Fatma | Zayed, Mohammed | Radey, Rasha | Ghallab, Ahmed | Hassan, Reham

Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury

2022 . Wehling, Lilija | Keegan, Liam | Fernández-Palanca, Paula | Hassan, Reham | Ghallab, Ahmed | Schmitt, Jennifer | Tang, Yingyue | Le Marois, Maxime | Roessler, Stephanie | Schirmacher, Peter | Kummer, Ursula | Hengstler, Jan | Sahle, Sven | Breuhahn, Kai

Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A

2022 . Hassan, Reham | González, Daniela | Hobloss, Zaynab | Brackhagen, Lisa | Myllys, Maiju | Friebel, Adrian | Seddek, Abdel-latif | Marchan, Rosemarie | Cramer, Benedikt | Humpf, Hans-Ulrich | Hoehme, Stefan | Degen, Gisela H | Hengstler, Jan | Ghallab, Ahmed

Contribution to the 3R Principle: Description of a Specimen-Specific Finite Element Model Simulating 3-Point-Bending Tests in Mouse Tibiae

2022 . Huang, Xiaowei | Nussler, Andreas | Reumann, Marie K. | Augat, Peter | Menger, Maximilian M. | Ghallab, Ahmed | Hengstler, Jan | Histing, Tina | Ehnert, Sabrina

Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity

Hepatobiliary Thyroid Hormone Deficiency Impacts Bile Acid Hydrophilicity and Aquaporins in Cholestatic C57BL/6J Mice

2022 . Kube-Golovin, Irina | Kowalczyk, Manuela | Hofmann, Ute | Ghallab, Ahmed | Hengstler, Jan | Führer, Dagmar | Zwanziger, Denise

Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity

Colchicine overdose impairs the capacity of Kupffer cells to clear foreign particles and endotoxins

2022 . Hassan, Reham | Myllys, Maiju | Brackhagen, Lisa | Hobloss, Zaynab | González, Daniela | Seddek, Abdel-latif | Friebel, Adrian Robert | Hoehme, Stefan | Marchan, Rosemarie | Trauner, Michael | Hengstler, Jan | Ghallab, Ahmed

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