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Simultaneous Brg1 Knockout and MYCN Overexpression in Cerebellar Granule Neuron Precursors Is Insufficient to Drive Tumor Formation but Temporarily Enhances their Proliferation and Delays their Migration

2021 . Holdhof, Dörthe | On, Ji Hoon | Schoof, Melanie | Göbel, Carolin | Schüller, Ulrich

Increased proliferation is associated with CNS invasion in meningiomas

2021 . Behling, Felix | Fodi, Christina | Wang, Sophie | Hempel, Johann-Martin | Hoffmann, Elgin | Tabatabai, Ghazaleh | Honegger, Jürgen | Tatagiba, Marcos | Schittenhelm, Jens | Skardelly, Marco

Selinexor decreases HIF-1α via inhibition of CRM1 in human osteosarcoma and hepatoma cells associated with an increased radiosensitivity

2021 . von Fallois, Moritz | Kosyna, Friederike Katharina | Mandl, Markus | Landesman, Yosef | Dunst, Jürgen | Depping, Reinhard

A metal-free salalen ligand with anti-tumor and synergistic activity in resistant leukemia and solid tumor cells via mitochondrial pathway

2021 . Hopff, Sina Marie | Wang, Qifang | Frias, Corazon | Ahrweiler, Marie | Wilke, Nicola | Wilke, Nathalie | Berkessel, Albrecht | Prokop, Aram

Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cerebral ischemia in mice

Dysregulated paired related homeobox 1 impacts on hepatocellular carcinoma phenotypes

2021 . Piorońska, Weronika | Nwosu, Zeribe Chike | Han, Mei | Büttner, Michael | Ebert, Matthias Philip | Dooley, Steven | Meyer, Christoph

Class I histone deacetylases (HDAC) critically contribute to Ewing sarcoma pathogenesis

2021 . Schmidt, Oxana | Nehls, Nadja | Prexler, Carolin | von Heyking, Kristina | Groll, Tanja | Pardon, Katharina | Garcia, Heathcliff D. | Hensel, Tim | Gürgen, Dennis | Henssen, Anton G. | Eggert, Angelika | Steiger, Katja | Burdach, Stefan | HS Richter, Günther

Molecular characterization of hematopoietic stem cells after in vitro amplification on biomimetic 3D PDMS cell culture scaffolds

2021 . Marx-Blümel, Lisa | Marx, Christian | Sonnemann, Jürgen | Weise, Frank | Hampl, Jörg | Frey, Jessica | Rothenburger, Linda | Cirri, Emilio | Rahnis, Norman | Koch, Philipp | Groth, Marco | Schober, Andreas | Wang, Zhao-Qi | Beck, James F.

IER2-induced senescence drives melanoma invasion through osteopontin

Prognostic role of proliferating CD8+ cytotoxic Tcells in human cancers

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