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Genetic mutations linked to Parkinson's disease differentially control nucleolar activity in pre-symptomatic mouse models

2017 . Evsyukov, Valentin | Domanskyi, Andrii | Bierhoff, Holger | Gispert, Suzana | Mustafa, Rasem | Schlaudraff, Falk | Liss, Birgit | Parlato, Rosanna

Synergistic killing of FLT3ITD-positive AML cells by combined inhibition of tyrosine-kinase activity and N-glycosylation

2017 . Tsitsipatis, Dimitrios | Kumar Jayavelu, Ashok | Müller, Jörg P. | Bauer, Reinhard | Schmidt-Arras, Dirk | Mahboobi, Siavosh | Schnöder, Tina M. | Heidel, Florian | Böhmer, Frank-D.

Protein phosphatase 4 regulatory subunit 2 (PPP4R2) is recurrently deleted in acute myeloid leukemia and required for efficient DNA double strand break repair

TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress

2016 . Pai, Govind M. | Zielinski, Alexandra | Koalick, Dennis | Ludwig, Kristin | wang, zhao-qi | Borgmann, Kerstin | Pospiech, Helmut | Rubio, Ignacio

Olfactory phenotypic expression unveils human aging

2016 . Mazzatenta, Andrea | Cellerino, Alessandro | Origlia, Nicola | Barloscio, Davide | Sartucci, Ferdinando | DI GIULIO, Camillo | Domenici, Luciano

CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins

2016 . Riecken, Lars Björn | Zoch, Ansgar | Wiehl, Ulrike | Reichert, Sabine | Scholl, Ingmar | Cui, Yan | Ziemer, Mirjana | Anderegg, Ulf | Hagel, Christian | Morrison, Helen

Epidermal Nbn deletion causes premature hair loss and a phenotype resembling psoriasiform dermatitis

2016 . Seidel, Philipp | Remus, Martina | Michael, Delacher | Grigaravicius, Paulius | Reuss, Davis E. | Frappart, Lucien | Deimling, Andreas von | Feuerer, Markus | Abdollahi, Amir | Frappart, Pierre-Olivier