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TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress

2016 . Pai, Govind M. | Zielinski, Alexandra | Koalick, Dennis | Ludwig, Kristin | wang, zhao-qi | Borgmann, Kerstin | Pospiech, Helmut | Rubio, Ignacio

Immunomodulation by memantine in therapy of Alzheimer's disease is mediated through inhibition of Kv1.3 channels and T cell responsiveness

2016 . Lowinus, Theresa | Bose, Tanima | Busse, Stefan | Busse, Mandy | Reinhold, Dirk | Schraven, Burkhart | Bommhardt, Ursula H. H.

Cellular apoptosis susceptibility (CAS) is linked to integrin β1 and required for tumor cell migration and invasion in hepatocellular carcinoma (HCC)

2016 . Winkler, Juliane | Roessler, Stephanie | Sticht, Carsten | DiGuilio, Amanda L. | Drucker, Elisabeth | Holzer, Kerstin | Eiteneuer, Eva | Herpel, Esther | Breuhahn, Kai | Gretz, Norbert | Schirmacher, Peter | Singer, Stephan | Ori, Alessandro

PARP activation promotes nuclear AID accumulation in lymphoma cells

2016 . Tepper, Sandra | Jeschke, Julia | Böttcher, Katrin | Schmidt, Angelika | Davari, Kathrin | Müller, Peter | Kremmer, Elisabeth | Hemmerich, Peter | Pfeil, Ines | Jungnickel, Berit

Practical aspects of NGS-based pathways analysis for personalized cancer science and medicine

2016 . Kotelnikova, Ekaterina A. | Pyatnitskiy, Mikhail | Paleeva, Anna | Kremenetskaya, Olga | Vinogradov, Dmitriy

Olfactory phenotypic expression unveils human aging

2016 . Mazzatenta, Andrea | Cellerino, Alessandro | Origlia, Nicola | Barloscio, Davide | Sartucci, Ferdinando | DI GIULIO, Camillo | Domenici, Luciano

Maternal butyrate supplementation induces insulin resistance associated with enhanced intramuscular fat deposition in the offspring

2016 . Huang, Yanping | Gao, Shixing | Chen, Jinglong | Zhao, Ruqian | Yang, Xiaojing | Albrecht, Elke

CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins

2016 . Riecken, Lars Björn | Zoch, Ansgar | Wiehl, Ulrike | Reichert, Sabine | Scholl, Ingmar | Cui, Yan | Ziemer, Mirjana | Anderegg, Ulf | Hagel, Christian | Morrison, Helen

Epidermal Nbn deletion causes premature hair loss and a phenotype resembling psoriasiform dermatitis

2016 . Seidel, Philipp | Remus, Martina | Michael, Delacher | Grigaravicius, Paulius | Reuss, Davis E. | Frappart, Lucien | Deimling, Andreas von | Feuerer, Markus | Abdollahi, Amir | Frappart, Pierre-Olivier

TNF induced cleavage of HSP90 by cathepsin D potentiates apoptotic cell death

2016 . Fritsch, Jürgen | Fickers, Ricarda | Klawitter, Jan | Särchen, Vinzenz | Zingler, Philipp | Adam, Dieter | Janssen, Ottmar | Krause, Eberhard | Schütze, Stefan