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EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma

The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression

Merkel cell carcinoma-derived exosome-shuttle miR-375 induces fibroblast polarization by inhibition of RBPJ and p53

2020 . Fan, Kaiji | Spassova, Ivelina | Gravemeyer, Jan | Ritter, Cathrin | Horny, Kai | Lange, Anja | Gambichler, Thilo | Ødum, Niels | Schrama, David | Schadendorf, Dirk | Ugurel, Selma | Becker, Jürgen

RASSF10 is frequently epigenetically inactivated in kidney cancer and its knockout promotes neoplasia in cancer prone mice

2020 . , Antje | Woods, Michelle L. | Küster, Miriam M. | Walesch, Sara K. | Braun, Thomas | Boettger, Thomas | Dammann, Reinhard H.

Loss of the nuclear Wnt pathway effector TCF7L2 promotes migration and invasion of human colorectal cancer cells

2020 . Wenzel, Janna | Rose, Katja | Haghighi, Elham Bavafaye | Lamprecht, Constanze | Rauen, Gilles | Freihen, Vivien | Kesselring, Rebecca | Boerries, Melanie | Hecht, Andreas

The p53/p73 - p21CIP1 tumor suppressor axis guards against chromosomal instability by restraining CDK1 in human cancer cells

2020 . Schmidt, Ann-Kathrin | Pudelko, Karoline | Boekenkamp, Jan-Eric | Berger, Katharina | Kschischo, Maik | Bastians, Holger

Entry and exit of chemotherapeutically-promoted cellular dormancy in glioblastoma cells is differentially affected by the chemokines CXCL12, CXCL16, and CX3CL1

2020 . Adamski, Vivian | Hattermann, Kirsten | Kubelt, Carolin | Cohrs, Gesa | Lucius, Ralph | Synowitz, Michael | Sebens, Susanne | Held-Feindt, Janka

BRAFV600E drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation

2020 . Reischmann, Nadine | Andrieux, Geoffroy | Griffin, Ricarda | Reinheckel, Thomas | Boerries, Melanie | Brummer, Tilman

Detection of pancreatic ductal adenocarcinoma with galectin-9 serum levels

2020 . Seifert, Adrian M. | Reiche, Charlotte | Heiduk, Max | Tannert, Anna | Meinecke, Ann-Christin | Baier, Stephanie | von Renesse, Janusz | Kahlert, Christoph | Distler, Marius | Welsch, Thilo | Reissfelder, Christoph | Aust, Daniela E. | Miller, George | Weitz, Jürgen | Seifert, Lena

ZBTB7A prevents RUNX1-RUNX1T1-dependent clonal expansion of human hematopoietic stem and progenitor cells

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