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Medicinal Polypharmacology in the Clinic – Translating the Polypharmacolome into Therapeutic Benefit

2024 . Rafehi, Muhammad | Möller, Marius | Ismail Al-Khalil, Wouroud | Stefan, Sven Marcel

Which Analysis Approach Is Adequate to Leverage Clinical Microdialysis Data? A Quantitative Comparison to Investigate Exposure and Response Exemplified by Levofloxacin

2021 . Busse, David | Schaeftlein, André | Solms, Alexander | Ilia, Luis | Michelet, Robin | Zeitlinger, Markus | Huisinga, Wilhelm | Kloft, Charlotte

Scaling Down Large-Scale Thawing of Monoclonal Antibody Solutions: 3D Temperature Profiles, Changes in Concentration, and Density Gradients

2021 . Bluemel, Oliver | Buecheler, Jakob W. | Hauptmann, Astrid | Hoelzl, Georg | Bechtold-Peters, Karoline | , Wolfgang

Evaluation of the Robustness of Therapeutic Drug Monitoring Coupled with Bayesian Forecasting of Busulfan with Regard to Inaccurate Documentation

2021 . Dadkhah, Adrin | Alihodzic, Dzenefa | Broeker, Astrid | Kröger, Nicolaus | Langebrake, Claudia | Wicha, Sebastian G.

Gel Strength of Hydrophilic Matrix Tablets in Terms of In Vitro Robustness

2021 . Goldoozian, Seyedreza | Mohylyuk, Valentyn | Dashevskiy, Andriy | Bodmeier, Roland

An Integrated Dialysis Pharmacometric (IDP) Model to Evaluate the Pharmacokinetics in Patients Undergoing Renal Replacement Therapy

2020 . Broeker, Astrid | Vossen, Matthias G. | Thalhammer, Florian | Wallis, Steven C. | Lipman, Jeffrey | Roberts, Jason A. | Wicha, Sebastian G.

Modelling Age-Related Changes in the Pharmacokinetics of Risperidone and 9-Hydroxyrisperidone in Different CYP2D6 Phenotypes Using a Physiologically Based Pharmacokinetic Approach

2020 . Kneller, Lisa Alina | Hempel, Georg

Physiologically Based Pharmacokinetic Models of Probenecid and Furosemide to Predict Transporter Mediated Drug-Drug Interactions

2020 . Britz, Hannah | Hanke, Nina | Taub, Mitchell E. | Wang, Ting | Prasad, Bhagwat | Fernandez, Éric | Stopfer, Peter | Nock, Valerie | Lehr, Thorsten

Thermodynamic, Spatial and Methodological Considerations for the Manufacturing of Therapeutic Polymer Nanoparticles

2020 . Maslanka Figueroa, Sara | Fleischmann, Daniel | Beck, Sebastian | Goepferich, Achim

A Biopredictive In Vitro Approach for Assessing Compatibility of a Novel Pediatric Hydrocortisone Drug Product within Common Pediatric Dosing Vehicles

2020 . Wollmer, Erik | Karkossa, Frank | Freerks, Lisa | Hetberg, Anna-Elena | Neal, Greg | Porter, John | Whitaker, Martin J. | Margetson, Daniel | Klein, Sandra

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